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Original
Articles
- Bunney, B.S.and Grace,
A.A.(1978) Acute and chronic haloperidol
treatment: Comparison of effects on nigral dopaminergic cell activity.
Life Sci. 23:1715-1728.
- Skirboll, L.R., Grace,
A.A.and Bunney, B.S.(1979) Dopamine auto- and
postsynaptic receptors: Electrophysiological evidence for
differential sensitivity to dopamine agonists. Science
206:80-82.
- Grace, A.A.and Bunney,
B.S.(1979) Paradoxical GABA excitation of nigral
dopaminergic cells: Indirect mediation through reticulata inhibitory
neurons. Eur. J. Pharmacol. 59:211-218.
- Grace, A.A.and Bunney,
B.S.(1980) Effects of baclofen on nigral
dopaminergic cell activity following acute and chronic haloperidol
treatment. Brain Res. Bull. 5 (Suppl.2):537-543.
- Grace, A.A., Hommer,
D.W.and Bunney, B.S.(1980) Peripheral and striatal
influences on nigral dopamine cells: Mediation by reticulata neurons.
Brain Res. Bull. 5 (Suppl.2):105-109.
- Bannon, M.J., Grace,
A.A., Bunney, B.S.and Roth, R.H.(1980) Evidence
for an irreversible interaction of bromocryptine with central dopamine
receptors. Naunyn-Schmiedeberg's Arch. Pharmacol. 312:37-41.
- Grace, A.A.and Bunney,
B.S.(1980) Nigral dopamine neurons:
Intracellular recording and identification using L-DOPA injection
combined with fluorescence histochemistry. Science 210:654-656.
- Skirboll, L.R., Grace,
A.A., Hommer, D.W., Rehfeld, J., Goldstein, M.,
Hökfelt, T.and Bunney, B.S.(1981) Peptide-monoamine
coexistence: Studies of the actions of cholecystokinin-like
peptide on the electrical activity of midbrain dopamine
neurons. Neuroscience 6:2111-2124.
- Grace, A.A.and Bunney,
B.S.(1983) Intracellular and extracellular
electrophysiology of nigral dopaminergic
neurons.I.Identification and characterization. Neuroscience
10:301-315.
- Grace, A.A.and Bunney,
B.S.(1983) Intracellular and extracellular
electrophysiology of nigral dopaminergic neurons.II.Action potential
generating mechanisms and morphological correlates. Neuroscience
10:317-331.
- Grace, A.A.and Bunney,
B.S.(1983) Intracellular and extracellular
electrophysiology of nigral dopaminergic neurons.III.Evidence for
electrical coupling. Neuroscience 10:333-348.
- Grace, A.A.(1983)
Nigral dopamine neurons: Identification,
characterization, and effects of autoreceptor stimulation. Yale
University dissertation.
- Chiodo, L.A., Bannon,
M.J., Grace, A.A., Roth, R.H.and Bunney,
B.S.(1984) Absence of autoreceptors on a subpopulation of mesocortical
dopamine neurons: Electrophysiological and biochemical
evidence. Neuroscience 12:1-16.
- Grace, A.A.and Bunney,
B.S.(1984) The control of firing pattern in
nigral dopamine neurons: Single spike firing. J. Neuroscience
4:2866-2876.
- Grace, A.A.and Bunney,
B.S.(1984) The control of firing pattern in
nigral dopamine neurons: Burst firing. J. Neuroscience
4:2877-2890.
- Grace, A.A.and Bunney,
B.S.(1985) Opposing effects of
striatonigral feedback pathways on midbrain dopamine cell
activity. Brain Res. 333:271-284.
- Grace, A.A.and Bunney,
B.S.(1985) Low doses of apomorphine elicit two
opposing influences on dopamine cell electrophysiology. Brain Res.
333:285-298.
- Grace, A.A.and
Llinás, R.(1985) Morphological artifacts
induced in intracellularly stained neurons by dehydration:
Circumvention using rapid dimethyl sulfoxide clearing.
Neuroscience 16:461-475.
- Grace, A.A. and
Bunney, B.S. (1986) Induction of depolarization block
in midbrain dopamine neurons by repeated administration of
haloperidol: Analysis using in vivo intracellular recording.
J. Pharmacol. Exp. Therapeut. 238: 1092-1100.
- Hollerman, J.R. and
Grace, A.A. (1989) Acute haloperidol administration
induces depolarization block of nigral dopamine neurons in rats after
partial dopamine lesions. Neuroscience Letters 96: 82-88.
- Grace, A.A. and Onn,
S.-P. (1989) Morphology and electrophysiological
properties of immunocytochemically identified rat dopamine neurons
recorded in vitro. J. Neuroscience 9: 3463-3481.
- Zigmond, M.J., Berger,
T.W., Grace, A.A. and Stricker, E.M. (1989)
Compensatory responses to nigrostriatal bundle injury: Studies with
6-hydroxydopamine in an animal model of Parkinsonism. Molecular and
Chemical Neuropathology 10: 185-200.
- Grace, A.A. (1990)
Evidence for the functional compartmentalization of
spike generating regions of rat midbrain dopamine neurons recorded in
vitro. Brain Res. 524: 31-41.
- Hollerman, J.R. and
Grace, A.A. (1990) The effects of
dopamine-depleting brain lesions on the electrophysiological activity
of rat substantia nigra dopamine neurons. Brain Research 533: 203-212.
- Zigmond, M.J.,
Abercrombie, E.D., Berger, T.W., Grace, A.A. and
Stricker, E.M. (1990) Compensations to nigrostriatal bundle injury:
Some clinical and basic implications. Trends in Neuroscience 13:
290-296.
- Grace, A.A. (1991)
Phasic versus tonic dopamine release and the
modulation of dopamine system responsivity: A hypothesis for the
etiology of schizophrenia. Neuroscience 41: 1-24.
- Grace, A.A. (1991)
Regulation of spontaneous activity and oscillatory
spike firing in rat midbrain dopamine neurons recorded in vitro.
Synapse 7: 221-234.
- Llinás, R.,
Grace, A.A. and Yarom, Y. (1991) In vitro
neurons in mammalian cortical layer 4 exhibit intrinsic oscillatory
activity in the 10 to 50 Hz frequency. Proc. Natl. Acad. Sci. USA 88:
897-901.
- Bunney, B.S., Chiodo,
L.A. and Grace, A.A. (1991) Midbrain dopamine
system electrophysiological functioning: A review and a new hypothesis.
Synapse 9: 79-94.
- Pucak, M.L. and Grace,
A.A. (1991) Partial dopamine depletions result
in an enhanced sensitivity of residual dopamine neurons to apomorphine.
Synapse 9: 144-155.
- Hollerman, J.R.,
Abercrombie, E.D. and Grace, A.A. (1992)
Electrophysiological, biochemical, and behavioral studies of acute
haloperidol-induced depolarization block of nigral dopamine neurons.
Neuroscience 47: 589-601.
- Nisenbaum, E.S.,
Grace, A.A. and Berger, T.W. (1992) Functionally
distinct subpopulations of striatal neurons are differentially
regulated by GABAergic and dopaminergic inputs. II. in vitro analysis.
Neuroscience 48: 579-593.
- Nisenbaum, E.S.,
Berger, T.W. and Grace, A.A. (1992) Presynaptic
modulation by GABAB receptors of glutamatergic excitation and GABAergic
inhibition of neostriatal neurons. J. Neurophysiol. 67: 477-481.
- Hollerman, J.R. and
Grace, A.A. (1992) Subthalamic nucleus cell firing
in the 6-OHDA-treated rat: Basal activity and response to haloperidol.
Brain Res. 590: 291-299.
- Smith, I.D. and Grace,
A.A. (1992) Role of the subthalamic nucleus in
the regulation of nigral dopamine neuron activity. Synapse 12: 287-303.
- Grace, A.A. (1992) The
depolarization block hypothesis of neuroleptic
action: Implications for the etiology and treatment of schizophrenia.
J. Neural Transm. 36 (suppl.): 91-131.
- O'Donnell, P. and
Grace, A.A. (1993) Physiological and morphological
properties of accumbens core and shell neurons recorded in vitro.
Synapse 13: 135-160.
- Nisenbaum, E.S.,
Berger, T.W. and Grace, A.A. (1993) Depression of
glutamatergic and GABAergic synaptic responses in striatal spiny
neurons by stimulation of presynaptic GABAB receptors. Synapse 14:
221-242.
- Grace, A.A. (1993)
Cortical regulation of subcortical dopamine systems
and its possible relevance to schizophrenia. J. Neural Transm. 91:
111-134.
- O'Donnell, P. and
Grace, A.A. (1993) Dopaminergic modulation of dye
coupling between neurons in the core and shell regions of the nucleus
accumbens. Journal of Neuroscience 13: 3456-3471.
- Onn, S.-P., Berger,
T.W. and Grace, A.A. (1994) Identification and
characterization of striatal cell subtypes using in vivo intracellular
recording in rats: I. Basic physiology and response to corticostriatal
fiber stimulation. Synapse 16: 161-180.
- Onn, S.-P., Berger,
T.W. and Grace, A.A. (1994) Identification and
characterization of striatal cell subtypes using in vivo intracellular
recording in rats: II. Membrane factors underlying paired pulse
response profiles. Synapse 16: 195-210.
- Onn, S.-P., Berger,
T.W. and Grace, A.A. (1994) Identification and
characterization of striatal cell subtypes using in vivo intracellular
recording and dye-labeling in rats: III. Morphological correlates and
compartmental localization. Synapse 16: 231-254.
- O'Donnell, P. and
Grace, A.A. (1994) Tonic D2-mediated attenuation of
cortical excitation in nucleus accumbens neurons recorded in vitro.
Brain Research 634: 105-112.
- Onn, S.-P. and Grace,
A.A. (1994) Dye coupling between rat striatal
neurons recorded in vivo: Compartmental organization and modulation by
dopamine. Journal of Neurophysiology 71: 1917-1934.
- Lavin, A. and Grace,
A.A. (1994) The modulation of dorsal thalamic cell
activity by the ventral pallidum: Its role in the regulation of
thalamocortical activity by the basal ganglia. Synapse 18: 104-127.
- Pucak, M.L. and Grace,
A.A. (1994) Evidence that systemically
administered dopamine antagonists activate dopamine neuron firing
primarily by blockade of somatodendritic autoreceptors. Journal of
Pharmacology and Experimental Therapeutics 371: 1181-1192.
- Grace, A.A. (1995) The
tonic/phasic model of dopamine system
regulation: Its relevance for understanding how stimulant abuse can
alter basal ganglia function. Drug and Alcohol Dependence 37: 111-129.
- O'Donnell, P. and
Grace, A.A. (1995) Synaptic interactions among
excitatory afferents to nucleus accumbens neurons: Hippocampal gating
of prefrontal cortical input. Journal of Neuroscience 15: 3622-3639.
- O'Donnell, P. and
Grace, A.A. (1995) Differential effects of subchronic
clozapine and haloperidol on dye coupling between neurons in the rat
striatal complex. Neuroscience 66: 763-767.
- Harden, D.G. and
Grace, A.A. (1995) Activation of dopamine cell firing
by repeated L-DOPA administration to dopamine-depleted rats: Its
potential role in mediating the therapeutic response to L-DOPA
treatment. Journal of Neuroscience 15: 6157-6166.
- Onn, S.-P. and Grace,
A.A. (1995) Repeated treatment with haloperidol
and clozapine exerts differential effects on dye coupling between
neurons in subregions of striatum and nucleus accumbens. Journal of
Neuroscience 15: 7024-7036.
- Lavin, A. and Grace,
A.A. (1996) Physiological properties of ventral
pallidal neurons recorded intracellularly in vivo. Journal of
Neurophysiology 75: 1432-1443.
- Pucak, M.L. and Grace,
A.A. (1996) Effects of haloperidol on the
activity and membrane physiology of substantia nigra dopamine neurons
recorded in vitro. Brain Research 713: 44-52.
- O’Donnell, P.
and Grace, A.A. (1996) Dopaminergic reduction
of excitability in nucleus accumbens neurons recorded in vitro.
Neuropsychopharmacology 15: 87-97.
- Grace, A.A., Bunney,
B.S., Moore, H. And Todd, C.L. (1997) Dopamine
cell depolarization block as a model for the therapeutic actions of
antipsychotic drugs. Trends in Neuroscience 20: 31-37.
- O’Donnell, P.
and Grace, A.A. (1997) Cortical afferents
modulate striatal gap junction permeability via nitric oxide.
Neuroscience 76: 1-5.
- O’Donnell,
P.,
Lavin, A., Enquist, L.W., Grace, A.A. and
Card, J.P. (1997) Interconnected parallel circuits between rat nucleus
accumbens and thalamus revealed by retrograde transynaptic transport of
pseudorabies virus. Journal of Neuroscience 17: 2143-2167.
- Mana, M.J. and Grace,
A.A. (1997) Chronic cold stress alters the basal
and evoked electrophysiological activity of rat locus coeruleus
neurons. Neuroscience 81: 1055-1064.
- Lavin, A. and Grace,
A.A. (1998) Response of the ventral
pallidal/mediodorsal thalamic system to antipsychotic drug
administration: Involvement of the prefrontal cortex.
Neuropsychopharmacology 18: 352-363.
- O’Donnell, P.
and Grace, A.A. (1998) Dysfunctions in multiple
interrelated systems as the neurobiological bases of schizophrenic
symptom clusters. Schizophrenia Bulletin 24: 267-283.
- Grace, A.A. and Moore,
H. (1998) Regulation of information flow in the
nucleus accumbens: A model for the pathophysiology of schizophrenia.
In: Origins and development of schizophrenia: Advances in experimental
psychopathology." Ed. M.F. Lenzenweger and R.H. Dworkin, American
Psychological Association Press, Washington, DC pp. 123-157.
- Harden, D.G., King,
D., Finlay, J. and Grace, A.A. (1998) Depletion of
dopamine in the prefrontal cortex decreases the basal
electrophysiological activity of mesolimbic dopamine neurons. Brain
Research 794: 96-102.
- O’Donnell, P.
and Grace, A.A. (1998) Phencyclidine interferes
with the hippocampal gating of nucleus accumbens neuronal activity in
vivo. Neuroscience 87: 823-830.
- Fienberg, A.A., Hiroi,
N., Mermelstein, P., Song, W.-J., Snyder, G.L.,
Nishi, A., Cheramy, A., O’Callaghen, J.P., Miller, D., Cole,
D.G., Corbett, R., Haile, C.N., Cooper, D.C., Onn, S.-P., Grace, A.A.,
Ouimet, C.C., White, F.J., Hyman, S.E., Surmeier, D.J., Girault, J.A.,
Nestler, E.J. and Greengard, P. (1998) DARPP-32, regulator of the
efficacy of dopaminergic transmission Science 281: 838-842.
- Moore, H., Todd, C.L,
and Grace, A.A. (1998) Striatal extracellular
dopamine levels in rats with haloperidol-induced depolarization block
of substantia nigra dopamine neurons. Journal of Neuroscience 18:
5068-5077.
- Lavin, A. and Grace,
A.A. (1998) Dopamine modulates the responsivity of
mediodorsal thalamic cells recorded in vitro. Journal of Neuroscience
18: 10566-10578.
- Todd, C.L. and Grace,
A.A. (1999) Interaction of benztropine and
haloperidol actions on rat substantia nigra dopamine cell
electrophysiological activity in vivo. Brain Research Bulletin 48:
219-222.
- Onn, S.-P. and Grace,
A.A. (1999) Alterations in electrophysiological
activity and dye coupling of striatal spiny and aspiny neurons in
dopamine-denervated rat striatum recorded in vivo. Synapse 33: 1-15.
- Newman, J. and Grace,
A.A. (1999) Binding across time: the selective
gating of frontal and hippocampal systems modulating working memory and
attentional states. Consciousness and Cognition 8: 196-212.
- Rosenkranz, J.A. and
Grace, A.A. (1999) Modulation of basolateral
amygdala neuronal firing and afferent drive by dopamine receptor
activation in vivo. Journal of Neuroscience 19: 11027-11039.
- Grace, A.A. (2000) The
tonic/phasic model of dopamine system regulation
and its implications for understanding alcohol and psychostimulant
craving. Addiction 95 (Supplement 2): S119-128.
- West, A.R. and Grace,
A.A. (2000) Striatal nitric oxide signaling
regulates the neuronal activity of midbrain dopamine neurons in vivo.
Journal of Neurophysiology 83: 1796-1808.
- Onn, S.-P. and Grace,
A.A. (2000) Amphetamine withdrawal alters
bistable states and cellular coupling in rat prefrontal cortex and
nucleus accumbens neurons recorded in vivo. Journal of Neuroscience 20:
2332-2345.
- Onn, S.P., West, A.R.
and Grace, A.A. (2000) Dopamine mediated
regulation of striatal neuronal and network interactions. Trends in
Neurosciences 23 (supplement) S48-S56.
- Moore, H., Rose, H.J..
and Grace, A.A. (2001) Chronic cold stress
reduces the spontaneous activity of ventral tegmental dopamine neurons.
Neuropsychopharmacology 24: 410-419.
- Drevets, W.C.,
Gautier, C., Price, J.C., Kupfer, D.J., Kinahan, P.E.,
Grace, A.A., Price, J.L, and Mathis, C. (2001) Amphetamine-induced
dopamine release in human ventral striatum correlates with euphoria.
Biological Psychiatry 49: 81-96.
- Lavin, A. and Grace,
A.A. (2001) Stimulation of D1-type dopamine
receptors enhances excitation in prefrontal cortical pyramidal neurons
in a state-dependent manner. Neuroscience 104: 335-346.
- Turner, M.S., Lavin,
A., Grace, A.A. and Napier, T.C. (2001) Regulation
of limbic information outflow by the subthalamic nucleus: Excitatory
amino acid projections to the ventral pallidum. Journal of Neuroscience
21: 2820-2832.
- Jedema, J.P., Finlay,
J.M., Sved, A.F. and Grace, A.A. (2001) Chronic
cold exposure potentiates corticotropin releasing hormone (CRH)-evoked
increases in electrophysiological activity of locus coeruleus neurons.
Biological Psychiatry 49: 351-359.
- Floresco, S.B., Todd,
C.L. and Grace, A.A. (2001) Glutamatergic
afferents from the hippocampus to the nucleus accumbens regulate
activity of ventral tegmental area dopamine neurons. Journal of
Neuroscience 21: 4915-4922.
- Rosenkranz, J.A. and
Grace, A.A. (2001) Dopamine attenuates prefrontal
cortical suppression of sensory inputs to the basolateral amygdala of
rats. Journal of Neuroscience 21: 4090-4103.
- West, A.R. and Grace,
A.A. (2002) Opposite Influences of endogenous
dopamine D1 and D2 receptor activation on activity states and
electrophysiological properties of striatal neurons: Studies combining
in vivo intracellular recordings and reverse microdialysis. Journal of
Neuroscience 22: 294-304.
- Rosenkranz, J.A. and
Grace, A.A. (2002) Cellular mechanisms of
infralimbic and prelimbic prefrontal cortical inhibition and
dopaminergic modulation of basolateral amygdala neurons in vivo.
Journal of Neuroscience 22: 324-337.
- West, A.R., Galloway,
M.P. and Grace, A.A. (2002) Regulation of
striatal dopamine neurotransmission by nitric oxide: Effector pathways
and signaling mechanisms. Synapse 44: 227-245.
- Rosenkranz, J.A. and
Grace, A.A. (2002) Dopamine-mediated modulation of
odour-evoked amygdala potentials during Pavlovian conditioning. Nature
417: 282-287.
- West, A.R., Moore, H.
and Grace, A.A. (2002) Direct examination of
local regulation of membrane activity in striatal and prefrontal
cortical neurons in vivo using simultaneous intracellular recording and
microdialysis. Journal of Pharmacology and Experimental Therapeutics
301: 867-877
- Singer, H.S.,
Szymanski, S., Giuliano, J., Yokoi, F., Dogan, A.S.,
Brasic, J.R., Grace, A.A. and Wong, D.F. (2002) Elevated intrasynaptic
dopamine release in Tourette Syndrome measured by PET. American Journal
of Psychiatry 159: 1329-1336.
- Moore, H. and Grace,
A.A. (2002) A role for electrotonic coupling in
the striatum in the expression of dopamine receptor-mediated
stereotypies. Neuropsychopharmacology 27: 980-992.
- Rosenkranz, J.A. and
Grace, A.A. (2002) Response: Mechanisms of
pavlovian fear conditioning. Trends in Neurosciences 25: 437-438.
- Jedema, H.P. and
Grace, A.A. (2003) Chronic exposure to cold stress
alters electrophysiological properties of locus coeruleus neurons
recorded in vitro. Neuropsychopharmacology 28:63-72.
- Floresco, S.B. and
Grace, A.A. (2003) Gating of hippocampal-evoked
activity in prefrontal cortical neurons by inputs from the mediodorsal
thalamus and ventral tegmental area. Journal of Neuroscience 23:
3930-3943.
- Onn, S.-P., Fienberg,
A.A., and Grace, A.A. (2003) Dopamine modulation
of membrane excitability in striatal spiny neurons is altered in
DARPP-32 knockout mice. Journal of Pharmacology and Experimental
Therapeutics 306: 870-879.
- Charara, A. and Grace,
A.A. (2003) Dopamine receptor subtypes
selectively modulate excitatory afferents from the hippocampus and
amygdala to rat nucleus accumbens neurons. Neuropsychopharmacology 28:
1412-1421.
- Floresco, S.B., West,
A.R., Ash, B., Moore, H. and Grace, A.A. (2003)
Afferent modulation of dopamine neuron firing differentially regulates
tonic and phasic dopamine transmission. Nature Neuroscience 6: 968-973.
- Rosenkranz, J.A.,
Moore, H. And Grace, A.A. (2003) The prefrontal
cortex regulates lateral amygdala neuronal plasticity and response to
previously conditioned stimuli. Journal of Neuroscience 23: 11054-11064.
- Grace, A.A. (2003)
Gating within limbic-cortical circuits and its
alteration in a developmental disruption model of schizophrenia.
Clinical Neuroscience Research 3: 333-338.
- West, A.R. and Grace,
A.A. (2004) The nitric oxide-guanylyl cyclase
signaling pathway modulates membrane activity states and
electrophysiological properties of striatal medium spiny neurons
recorded in vivo. Journal of Neuroscience 24: 1924 - 1935.
- Floresco, S.B., West,
A.R. and Grace, A.A. (2004) Extrasynaptic
dopamine and phasic neuronal activity. Reply. Nature Neuroscience 7:
199.
- Thompson, J.L.,
Pogue-Geile, M.F. and Grace, A.A. (2004) Developmental
pathology, dopamine, and stress: A model for the age of onset of
schizophrenia symptoms. Schizophrenia Bulletin 30: 875-900.
- Fiore, M., Grace,
A.A., Korf, J., Stampachiacchiere, B. And Aloe, L.
(2004) Impaired brain development in the rat following prenatal
exposure to methylazoxymethanol acetate at gestational day 17 and
neurotrophin distribution. NeuroReport 15: 1791-1795.
- Bilder, R.M., Volavka,
J., Lachman, H.M. and Grace, A.A. (2004) The
catechol-O-methyltransferase polymorphism: Relations to the
tonic-phasic dopamine hypothesis and neurocognitive phenotypes.
Neuropsychopharmacology 29: 1943-1961.
- Jedema, H.P. and
Grace, A.A. (2004) Corticotropin-releasing hormone
directly activates noradrenergic neurons of the locus coeruleus
recorded in vitro. Journal of Neuroscience 24: 9703-9713.
- Kroner, S.,
Rosenkranz, J.A., Grace, A.A. and Barrionuevo, G. (2005)
Dopamine modulates excitability of basolateral amygdala neurons in
vitro. Journal of Neurophysiology 93: 1598-1610.
- Lodge, D.L. and Grace,
A.A. (2005) Acute and chronic Corticotropin
Releasing Factor 1 receptor blockade inhibits cocaine-induced dopamine
release: Correlation with dopamine neuron activity. Journal of
Pharmacology and Experimental Therapeutics 314: 201-206
- Lavin, A., Moore, H.,
and Grace, A.A. (2005) Prenatal disruption of
neocortical development alters prefrontal cortical neuron responses to
dopamine in adult rat. Neuropsychopharmacology 30, 1426-1435.
- Goto, Y. and Grace,
A.A. (2005) Dopaminergic modulation of limbic and
cortical drive of nucleus accumbens in goal-directed behavior.
Nature-Neuroscience 8: 805-812.
- Correll, C.M.,
Rosenkranz, J.A. and Grace, A.A. (2005) Chronic cold
stress alters prefrontal cortical modulation of amygdala neuronal
activity in rats. Biological Psychiatry 58: 382-391.
- Lisman, J. and Grace,
A.A. (2005) The hippocampal-VTA loop: control of
entry into long-term memory. Neuron 46: 703-713.
- Laviolette, S.R.,
Lipski W.J. and Grace, A.A. (2005) A subpopulation of
neurons in the medial prefrontal cortex encode emotional learning with
burst and frequency codes through a dopamine D4 receptor-dependent
basolateral amygdala input. Journal of Neuroscience 25: 6066-6075.
- Goto, Y. and Grace,
A.A. (2005) Dopamine-dependent interactions between
limbic and prefrontal cortical synaptic plasticity in the nucleus
accumbens: Disruption by cocaine sensitization. Neuron 47: 255-266.
- Floresco, S.B., Geyer,
M.A., Gold, L.H., and Grace, A.A. (2005)
Developing predictive models and establishing a preclinical trials
network for assessing treatment effects on cognition in animals.
Schizophrenia Bulletin 31: 888-894.
- Onn, S.-P., Wang,
X.-B., Lin M. and Grace, A.A. (2006) Dopamine D1 and
D4 receptors differentially modulate recurrent excitatory synapses in
prefrontal cortical pyramidal neurons. Neuropsychopharmacology 31:
318-338.
- Miner, L.H., Jedema,
H.P., Moore, F.W., Blakely, R.D., Grace, A.A. and
Sesack, S.R. (2006) Chronic stress increases the plasmalemmal
distribution of the norepinephrine transporter and the co-expression of
tyrosine hydroxylase in norepinephrine axons in the prefrontal cortex.
Journal of Neuroscience 26: 1571-1578.
- Lodge, D.J. and Grace,
A.A. (2006) The laterodorsal tegmental nucleus
is essential for burst firing of dopamine neurons in the rat VTA.
Proceedings of the National Academy of Sciences, USA 1003 (13)
5167-5172.
- Rosenkranz, J.A.,
Buffalari, D.M. and Grace, A.A. (2006) Opposing
influence of basolateral amygdala and footshock stimulation on neurons
of the central amygdala. Biological Psychiatry 59: 801-811.
- Laviolette, S.R. and
Grace, A.A. (2006) Cannabinoids dramatically
potentiate neuronal emotional learning in the medial prefrontal cortex
through basolateral amygdala inputs Journal of Neuroscience 26:
6458-6468.
- Lodge, D.J. and Grace,
A.A. (2006) The hippocampus modulates dopamine
neuron responsivity by regulating the intensity of phasic neuron
activation. Neuropsychopharmacology 31: 1356-1361.
- Moore, H., Ghajarnia,
M.E., Jentsch, J.D., Geyer, M.A. and Grace, A.A.
(2006) A Neurobehavioral Systems Analysis of Adult Rats Exposed to
Methylazoxymethanol Acetate on E17: Implications for the Neuropathology
of Schizophrenia. Biological Psychiatry 60: 253-264.
- Goto, Y. and Grace,
A.A. (2006) Alterations in prefrontal cortical
activity and plasticity in adult rats with disruption of cortical
development. Biological Psychiatry 60: 1259-1267.
- Kawashima, H., Izaki,
Y., Grace, A.A., and Takita, M. (2006)
Cooperativity between hippocampal-prefrontal short-term plasticity
through associative long-term potentiation. Brain Research 1109: 37-44.
- Wong, D.F., Kuwabara,
H., Schretlin, D., Bonson, K., Zhou, Y., Nandi,
A., Brasic, J., Kimes, A.S., Maris M.A., Kumar, A., Contoreggi, C.,
Links, J., Ernst, M., Rousset, O., Zukin, S., Grace, A.A., Rohde, C.,
Jasinski, D.R., Gjedde, A. and London, E.D. (2006) Increased occupancy
of dopamine receptors in human striatum during cue-elicited cocaine
craving. Neuropsychopharmacology 31: 2716-2727.
- Grace, A.A., Floresco,
S.B., Goto, Y. and Lodge, D.J. (2007) The
regulation of dopamine neuron firing and the control of goal-directed
behaviors. Trends in Neurosciences 30:220-227.
- Lodge, D.J. and Grace,
A.A. (2007) Aberrant hippocampal activity
underlies the dopamine dysregulation in an animal model of
schizophrenia. Journal of Neuroscience 27: 11424-11430.
- Goto, Y. and Grace,
A.A. (2007) The Yin and Yang of Dopamine Release: A
New Perspective. Neuropharmacology 53: 583-587.
- Buffalari, D.M. and
Grace, A.A. (2007) Noradrenergic modulation of
basolateral amygdala neuronal activity: Opposing influences of alpha-2
and beta receptor activation. Journal of Neuroscience 27: 12358-12366.
- McCracken, C.B. and
Grace, A.A. (2007) High-frequency deep brain
stimulation of the nucleus accumbens region suppresses neuronal
activity and selectively modulates afferent drive in rat orbitofrontal
cortex in vitro. Journal of Neuroscience 27: 12601-12610.
- Bissière,
S.,
Plachta, N., McAllister, K.H., Hoyer, D.,
Olpe, H.-R., Grace, A.A. and Cryan, J.F. (2008) The rostral anterior
cingulate cortex modulates the efficiency of amygdala-dependent fear
learning. Biological Psychiatry 63: 821-831.
- Onn, S.-P., Lin, M.,
Liu, J. and Grace, A.A. (2008) Dopamine
DARPP-32-dependent modulation of prefrontal cortical input and
intercellular coupling in mouse accumbens spiny and aspiny neurons.
Neuroscience 151: 802-816.
- Wong, D.F., Brasic,
J., Singer, H., Schretlen, D., Kuwabara, H., Zhou,
Y., Nandi, A., Maris, M., Alexander, M., Ye, W., Rousset, O., Kumar,
A., Szabo, Z., Gjedde, A. and Grace, A.A. (2008) Mechanisms of dopamine
and serotonin in Tourette syndrome: Clues from an in vivo
neurochemistry study with PET. Neuropsychopharmacology 33: 1239-1251.
- Lisman, J.E., Coyle,
J.T., Greene, R.W., Javitt, D.C., Benes, F.M.,
Heckers, S. and Grace, A.A. (2008) Circuit-based framework for
understanding neurotransmitter and risk gene interactions in
schizophrenia Trends in Neurosciences 31: 234-242.
- Jedema, H.P..P, Gold,
S.J., Gonzalez-Burgos, G., Sved, A.F., Tobe,
B.J., Wensel, T.G. and Grace, A.A. (2008) Chronic cold exposure
increases RGS7 expression and decreases ?2-autoreceptor-mediated
inhibition of noradrenergic locus coeruleus neurons. European Journal
of Neuroscience 27: 2433-2443.
- Krystal JH, Carter CS,
Geschwind D, Manji HK, March JS, Nestler EJ,
Zubieta JK, Charney DS, Goldman D, Gur RE, Lieberman JA, Roy-Byrne P,
Rubinow DR, Anderson SA, Barondes S, Berman KF, Blair J, Braff DL,
Brown ES, Calabrese JR, Carlezon WA Jr, Cook EH Jr, Davidson RJ, Davis
M, Desimone R, Drevets WC, Duman RS, Essock SM, Faraone SV, Freedman R,
Friston KJ, Gelernter J, Geller B, Gill M, Gould E, Grace AA, Grillon
C, Gueorguieva R, Hariri AR, Innis RB, Jones EG, Kleinman JE, Koob GF,
Krystal AD, Leibenluft E, Levinson DF, Levitt PR, Lewis DA, Liberzon I,
Lipska BK, Marder SR, Markou A, Mason GF, McDougle CJ, McEwen BS,
McMahon FJ, Meaney MJ, Meltzer HY, Merikangas KR, Meyer-Lindenberg A,
Mirnics K, Monteggia LM, Neumeister A, O'Brien CP, Owen MJ, Pine DS,
Rapoport JL, Rauch SL, Robbins TW, Rosenbaum JF, Rosenberg DR, Ross CA,
Rush AJ, Sackeim HA, Sanacora G, Schatzberg AF, Shaham Y, Siever LJ,
Sunderland T, Tecott LH, Thase ME, Todd RD, Weissman MM, Yehuda R,
Yoshikawa T, Young EA, McCandless R (2008) It is time to take a stand
for medical research and against terrorism targeting medical
scientists. Biological Psychiatry 63: 725-727
- Goto, Y. and Grace,
A.A. (2008) Dopamine modulation of
hippocampal-prefrontal cortical interaction drives memory-guided
behavior. Cerebral Cortex 18: 1407 - 1414.
- McGinty, V.B. and
Grace, A.A. (2008) Selective activation of medial
prefrontal-to-accumbens projection neurons by amygdala stimulation and
pavlovian conditioned stimuli. Cerebral Cortex 18: 1961-1972
- Lodge, D.J. and Grace,
A.A. (2008) Augmented hippocampal drive of
mesolimbic dopamine neurons: A mechanism of psychostimulant
sensitization. Journal of Neuroscience 28 7876-7882.
- Grace, A.A. (2008)
Physiology of the normal and dopamine-depleted basal
ganglia: Insights into L-DOPA pharmacotherapy. Movement Disorders 25S3:
S560-S569.
- Belujon, P. and Grace,
A.A. (2008) Critical role of the prefrontal
cortex in the regulation of hippocampus-accumbens information flow.
Journal of Neuroscience 28: 9797-9805.
- Goto, Y, and Grace,
A.A. (2008) Limbic and cortical information
processing in the nucleus accumbens. Trends in Neurosciences 31:
552-558.
- Sengupta, S.M.,
Grizenko, N., Schmitz, N., Schwartz, G., Bellingham,
J., Polotskaia, A., Ter Stepanian, M., Goto, Y., Grace, A.A. and
Joober, R. (2008) COMT Val 108/158Met polymorphism modulates
task-oriented behaviour in children with ADHD Neuropsychopharmacology
33: 3069-3077.
- Buffalari, D.M. and
Grace, A.A. (2009) Chronic cold stress increases
excitatory effects of norepinephrine on spontaneous and evoked activity
of basolateral amygdala neurons. International Journal of
Neuropsychopharmacology 12: 95-107.
- Valenti, O. and Grace,
A.A. (2009) Entorhinal cortex modulates the
activity states of electrophysiologically characterized medial
prefrontal cortical neurons. Cerebral Cortex 19: 658-674.
- Lodge, D.J., Behrens,
M.M. and Grace, A.A. (2009) A loss of
parvalbumin-containing interneurons is associated with diminished
oscillatory activity in an animal model of schizophrenia. Journal of
Neuroscience 29:2344-2354.
- McGinty, V.B. and
Grace, A.A. (2009) Timing-dependent regulation of
evoked spiking in nucleus accumbens neurons by integration of limbic
and prefrontal cortical inputs. Journal of Neurophysiology 101:
1823-1835.
- McCracken, C.B. and
Grace, A.A. (2009) Nucleus accumbens deep brain
stimulation produces region-specific alterations in local field
potential oscillations and evoked responses in vivo. Journal of
Neuroscience 29: 5354-5363.
- McGinty, V.B. and
Grace, A.A. (2009) Activity-dependent depression of
medial prefrontal cortex inputs to accumbens neurons by the basolateral
amygdala. Neuroscience 162: 1429-1436.
- Buffalari, D.M. and
Grace, A.A. (2009) Anxiogenic modulation of
spontaneous and evoked neuronal activity in the basolateral amygdala.
Neuroscience 163: 1069-1077.
- Kumra, S. Asarnow, R.,
Grace, A.A., Keshavan, M., McClellan, J.,
Sikich, L. and Wagner, A. (2009) From bench to bedside: Translating new
research from neuroimaging and genetics into treatment development for
early-onset schizophrenia. Early Intervention in Psychiatry 3(4)
178-188.
- Valenti, O. and Grace,
A.A. (2010) Antipsychotic drug-induced increases
in ventral tegmental area dopamine neuron population activity via
activation of the nucleus accumbens-ventral pallidal pathway.
International Journal of Neuropsychopharmacology 13(7): 845-60.
- Grace, A.A. (2010)
Ventral hippocampus, interneurons and schizophrenia:
A new understanding of the pathophysiology of schizophrenia and its
implications for treatment and prevention. Current Directions in
Psychological Science 19: 232-237.
- Belujon, P., Lodge,
D.J. and Grace, A.A. (2010) Aberrant striatal
plasticity is specifically associated with dyskinesias following L-DOPA
treatment. Movement Disorders 25: 1568-1576.
- Lodge, D.J. and Grace,
A.A. (2010) Developmental pathology, dopamine,
stress and schizophrenia. International Journal of Developmental
Neuroscience (in press).
- Lipski, W.J. and
Grace, A.A. (2010) Ventral hippocampal-medial
prefrontal cortical synaptic plasticity is selectively modified by
contextual fear conditioning. (submitted).
- Cifelli, P. and Grace,
A.A. (2010) Pilocarpine induced temporal lobe
epilepsy in the rat is associated with increased dopamine neuron
activity. (submitted).
- Moses-Kolko, E.L.,
Meltzer, C.C., Lanza di Scalea, T., Kaye, W., Price,
J.C., Grace, A.A., Berga, S.L., Mathis, C.A., Drevets, W.C., Hanusa,
B.H., Becker, C. and Wisner, K.L. (2010) Relationship of depression and
[11C]raclopride binding to D2/3 receptors is moderated by postpartum
status in unipolar depressed women. (submitted).
- Gill, K.M. and Grace,
A.A. (2010) Heterogeneous processing of amygdala
and hippocampal inputs in the rostral and caudal subregions of the
nucleus accumbens (submitted).
- Valenti, O., Lodge,
D.J. and Grace, A.A. (2010) Aversive stimuli alter
ventral tegmental area dopamine neuron activity via a common action in
the ventral hippocampus (submitted).
- Lodge, D.J. and Grace,
A.A. (2010) Divergent activation of ventromedial
and ventrolateral dopamine systems in animal models of amphetamine
sensitization and schizophrenia. (submitted).
Book
Chapters and Reviews
- Grace, A.A.(1977)
Techniques in Neurobiological Research. Allegheny
College Printing, Meadville, PA. pp.1-165.
- Bunney, B.S.and
Grace,
A.A.(1979) Effects of chronic haloperidol
treatment on nigral dopaminergic cell activity. In:
Catecholamines: Basic and Clinical Frontiers. Eds.E.Usdin,
I.J.Kopin and J.Barchas, Pergamon Press, New York, pp.666-668.
- Bunney, B.S.,
Grace,
A.A.and Hommer, D.W.(1980) Changing concepts of
nigral dopamine system function within the basal ganglia. J. Neural
Trans. (Suppl.16):17-23.
- Bunney, B.S.,
Skirboll,
L.R.and Grace, A.A.(1980) Acute and chronic
haloperidol treatment: Effects on nigrostriatal dopaminergic
system activity. Adv. Biochem. Psychopharmacol. 24:267-273.
- Skirboll, L.R.,
Hökfelt, T., Grace, A.A., Hommer, D.W.,
Rehfeld, J.F., Markey, K., Goldstein, M.and Bunney, B.S.(1981) The
co-existence of dopamine and a CCK-like peptide in a
subpopulation of midbrain neurons: Immunocytochemical and
electrophysiological studies. In: Apomorphine and other
Dopaminomimetics. Vol. 1: Basic Pharmacology. Eds.G.L.Gessa and
G.U.Corsini. Raven Press, New York, pp.65-77.
- Bunney, B.S.,
Grace,
A.A., Hommer, D.W.and Skirboll, L.R.(1982) Effect
of cholecystokinin on the activity of midbrain dopaminergic neurons.
In: Advances in Biochemical Psychopharmacology, Vol. 32. Eds.E.Costa
and M.Trabucci. Raven Press, New York, 429-437.
- Grace, A.A.and
Bunney,
B.S.(1984) Nigral dopaminergic neurons:
Extracellular and intracellular electrophysiological
characteristics. In: Catecholamines: Neuropharmacology and
Central Nervous System - Theoretical Aspects. Eds.E.Usdin, A.Carlsson,
A.Dahlström and J.Engel. Alan R.Liss, Inc.,New York, 323-332.
- Bannon, M.J.,
Chiodo,
L.A., Bunney, E.B., Wolf, M.E., Grace, A.A.,
Bunney, B.S.and Roth, R.H.(1984) In vivo biochemical and
electrophysiological studies on the distribution and
pharmacology of dopamine autoreceptors. In:Catecholamines:
Neuropharmacology and Central Nervous System - Theoretical Aspects.
Eds.E.Usdin, A.Carlsson, A.Dahlström and J.Engel. Alan R.Liss,
Inc., New York, 25-36.
- Grace, A.A.and
Bunney,
B.S. (1984) Striatal modulation of dopamine
neuron firing. Clinical Neuropharmacol. 7 (Suppl.1):64-65.
- Bunney, B.S.,
Grace,
A.A.and Meltzer, L.T.(1984) Midbrain
dopaminergic neurons: A new model of their functioning?
Clinical Neuropharmacol. 7 (Suppl.1):92-93.
- Grace, A.A.and
Bunney,
B.S.(1985) Dopamine. In: Neurotransmitter
Actions in the Vertebrate Nervous System. Eds.J.L.Barker and
M.A.Rogawski, Plenum Publishing Corp., New York, 285-319.
- Bunney, B.S.,
Chiodo,
L.A., Grace, A.A.and Schenk, J.O.(1985) In vivo
effects of acute and chronic antipsychotic drug administration
on midbrain dopaminergic neuron activity. In: Behavioral Pharmacology:
The Current Status. Eds.R.Balster and L.Seiden. Alan R.Liss, Inc., New
York, 205-220.
- Grace, A.A.
(1987)
Commentary: An electrophysiologist's eye view of the
basal ganglia. Behavioral Brain Sci. 10: 197-245.
- Grace, A.A.
(1987) The
regulation of dopamine neuron activity as
determined by in vivo and in vitro intracellular recordings. In: The
Neurophysiology of Dopamine Systems. Eds. Chiodo, L.A. and Freeman,
A.S. Lake Shore Publications, Detroit, pp. 1-67.
- Grace, A.A.
(1988) In
vivo and in vitro intracellular recordings from
dopamine neurons. Annals of the New York Academy of Sciences: The
Mesocorticolimbic Dopamine System Vol. 537: 51-76.
- Berger, T.W.,
Nisenbaum, E.S., Onn, S.-P. and Grace, A.A. (1990)
Pharmacological and morphological properties of two functionally
distinct subpopulations of striatal neurons. In: The Basal Ganglia III.
Ed. G. Bernardi, M.B. Carpenter, G. DiChiara, M. Morelli and P.
Stanzione, Plenum Press, New York; Advances in Behavioral Biology 60:
335-345.
- Grace, A.A.
(1991) The
modulation of dopamine system responsivity by
cortically regulated extracellular dopamine levels: A hypothesis for
the etiology of schizophrenia. Posters in Neuroscience 1: 3-8.
- Smith, I.D. and
Grace,
A.A. (1991) Subthalamic nucleus afferents to the
substantia nigra regulate dopamine neuron burst firing. Posters in
Neuroscience 1: 25-28.
- Nisenbaum, E.S.,
Grace,
A.A. and Berger, T.W. (1991) Differential
contribution of D1 and D2 dopaminergic receptors to the response
properties of two functionally distinct subpopulations of striatal
neurons. Posters in Neuroscience 1: 59-66.
- Zigmond, M.J.,
Abercrombie, E.D., Berger, T.W., Grace, A.A. and
Stricker, E.M. (1993) Compensatory responses to partial loss of
dopaminergic neurons: Studies with 6-hydroxydopamine. In: Current
Concepts in Parkinson's Disease Research. Ed. J.S. Schneider &
M. Gupta, Hogrefe & Huber Publishers, Toronto, pp. 99-140.
- Onn, S.-P.,
Pucak, M.L.
and Grace, A.A. (1993) Lucifer yellow dye
labeling of living nerve cells and subsequent immunoperoxidase staining
with Lucifer yellow antiserum. Neuroscience Protocols: 93-050-17.
- Pucak, M.L. and
Grace,
A.A. (1994) The regulation of substantia nigra
dopamine neurons. Critical Reviews in Neurobiology 9: 67-89.
- Grace, A.A. and
Bunney,
B.S. (1995) Electrophysiology. In: American
Psychiatric Press Textbook of Psychopharmacology. Ed. C.B. Nemeroff and
A.F. Schatzberg, American Psychiatric Press, Washington, D.C. pp. 65-79.
- Grace, A.A. and
Bunney,
B.S. (1995) Electrophysiological properties of
midbrain dopamine neurons. In: Psychopharmacology: The Fourth
Generation of Progress. Ed. F.E. Bloom and D.J. Kupfer, Raven Press,
New York, pp. 163-177.
- O’Donnell,
P.
and Grace, A.A. (1996) Basic neurophysiology of
antipsychotic drug action. Chapter 16. In: Handbook of Experimental
Pharmacology: Antipsychotics. Ed. J.G. Csernansky, Springer-Verlag,
Heidelberg, pp. 163-202.
- Grace, A.A.
(1996)
Thalamocortical aspects of consciousness from the
perspective of a neurobiologist: A commentary on J. Newman's
"Thalamocortical Foundations of Conscious Experience" E-Seminar at URL:
http://server.phil.vt.edu/ASSC/newman/grace.html
- Grace, A.A.
(1996)
Chapter 13: Gating of information flow through
limbic and thalamocortical systems: Implications for the
pathophysiology of schizophrenia. In: Schizophrenia: Latest Advances in
Understanding and Drug Development. Ed. L. Dirks, IBC Biomedical
Library, Southborough, MA pp. 1.3.1-1.3.25.
- Grace, A.A.,
Moore, H.
and O’Donnell, P. (1997) The
modulation of corticoaccumbens transmission by limbic afferents and
dopamine: A model for the pathophysiology of schizophrenia. In:
Catecholamines: Bridging Basic Science with Clinical Medicine; Advances
in Pharmacology 42: 721-724.
- Grace, A.A.,
Gerfen
C.R. and Aston-Jones, G. (1997) Theme F:
Catecholamines in the central nervous system: Overview. In:
Catecholamines: Bridging Basic Science with Clinical Medicine; Advances
in Pharmacology 42: 655-670.
- Grace, A.A.,
Todd, C.L.
and Moore, H. (1997) Glutamatergic effects and
depolarization block - Reply. Trends in Neurosciences 20: 394-395.
- Grace, A.A.
(1997)
Temporal correlates of binding and associations: Are
they system-specific? A commentary on Engel, A.K., Fries, P.,
Roelfsema, R., Konig, P. and Singer, W. ATemporal binding, binocular
rivalry, and consciousness. E-Seminar at URL:
http://server.phil.vt.edu/ASSC/engel/grace1.html
- Grace, A.A. and
Bunney,
B.S. (1998) Electrophysiology. In: American
Psychiatric Press Textbook of Psychopharmacology, Second Edition. Ed.
C.B. Nemeroff and A.F. Schatzberg, American Psychiatric Press,
Washington, D.C. pp. 75-88.
- Czernansky, J.G.
and
Grace, A.A. (1998) Editors, New Pathophysiological
Models of Schizophrenia. Special Issue of Schizophrenia Bulletin Volume
24 (2) pp. 185-316.
- Czernansky, J.G.
and
Grace, A.A. (1998) New models of the
pathophysiology of schizophrenia: Editors’ introduction.
Schizophrenia Bulletin 24: 185-187.
- Grace, A.A.
(1998)
Multiple Mechanisms for the Regulation and Gating of
Affect within the Basal Ganglia and Thalamocortical System. E-Seminar
at URL: http://www.phil.vt.edu/ASSC/watt/grace1.html
- O’Donnell,
P.
and Grace, A.A. (1999) Disruption of
information flow within cortical-limbic circuits and the
pathophysiology of schizophrenia. Review of Psychiatry, Vol. 18:
Schizophrenia in a Molecular Age, Ed. C.A. Tamminga, American
Psychiatric Press, Inc., Washington, DC, pp. 109-140.
- Todd, C.L. and
Grace,
A.A. (1999) Modulation of ventral tegmental area
dopamine cell activity by the ventral subiculum and entorhinal cortex.
Annals of the New York Academy of Sciences: Advancing from the Ventral
Striatum to the Extended Amygdala. Vol. 877: 688-690.
- O’Donnell,
P., Green, J., Pabello, N., Lewis, B.L. and Grace,
A.A. (1999) Modulation of cell firing in the nucleus accumbens. Annals
of the New York Academy of Sciences: Advancing from the Ventral
Striatum to the Extended Amygdala. Vol. 877: 157-175.
- Moore, H., West,
A.R.
and Grace, A.A. (1999) The regulation of
forebrain dopamine neurotransmission: Relevance to the pathophysiology
of schizophrenia. Biological Psychiatry 46: 40-55.
- Grace, A.A.
(2000)
Gating of information flow within the limbic system
and the pathophysiology of schizophrenia. Proceedings from the Nobel
Symposium - Schizophrenia: Pathophysiological Mechanisms. Brain
Research Reviews 31: 330-341.
- West, A.R. and
Grace,
A.A. (2001) The role of frontal-subcortical
circuits in the pathophysiology of schizophrenia. In:
Frontal-Subcortical Circuits in Neurology and Psychiatry, Ed. D.G.
Lichter, Guilford Press, New York 372-400.
- Grace, A.A.
(2001)
Psychostimulant actions on dopamine and limbic
system function: Relevance to the pathophysiology and treatment of
ADHD. In: Stimulant Drugs and ADHD: Basic and Clinical Neuroscience. M.
V. Solanto, A.F.T. Arnsten and F.X. Castellanos (Eds.) Oxford
University Press, New York 134-157.
- Grace, A.A.
(2002)
Dopamine. In: Neuropsychopharmacology: The Fifth
Generation of Progress. Ed. D. Charney, J. Coyle, K. Davis and C.
Nemeroff. Lippincott, Williams and Wilkins, Raven Press, New York pp.
119-132.
- Rosenkranz, J.A.
and
Grace, A.A. (2002) Regulation of conditioned
responses of basolateral amygdala neurons. Physiology and Behavior 77:
489-493.
- Rosenkranz, J.A.
and
Grace, A.A. (2003) Affective conditioning in the
basolateral amygdala of anesthetized rats is modulated by dopamine and
prefrontal cortical inputs. In: The Amygdala in Brain Function. Annals
of the New York Academy of Sciences 985: 488-491.
- Grace, A.A.,
Rosenkranz, J.A. and West, A.R. (2003) Electrophysiology.
In: American Psychiatric Press Textbook of Psychopharmacology, Third
Edition. Ed. C.B. Nemeroff and A.F. Schatzberg, American Psychiatric
Press, Washington, D.C. pp. 89-103.
- West, A.R.,
Floresco,
S.B., Charara, A., Rosenkranz J.A. and Grace,
A.A. (2003) Electrophysiological interactions between striatal
glutamatergic and dopaminergic systems. In Glutamate and Disorders of
Cognition and Motivation. Vol. 1003, Annals of the New York Academy of
Sciences; ed. B. Moghaddam & M.E. Wolf. pp 53-74.
- Grace, A.A.
(2003)
Forebrain dopamine systems: can they help us to
understand psychosis? European Psychiatry 18: 27s-31s.
- Grace, A.A.
(2004)
Schizophrenia represents a failure to regulate
dopamine systems. In: Schizophrenia - Challenging the Orthodox. Ed: C.
McDonald, K. Schulze, R. M. Murray, & P. Wright. Martin Dunitz
Publishers, London, UK pp. 137-144.
- Grace, A.A.
(2004)
Developmental dysregulation of the dopamine system
and the pathophysiology of schizophrenia. In Neurodevelopment and
Schizophrenia. M. Keshavan, JL Kennedy & R.M. Murray, eds.
Cambridge University Press pg. 273-294.
- Grace, A.A.
(2006)
Disruption of cortico-limbic interaction as a
substrate for comormidity. Neurotoxicity Research 10: 93-101.
- Agid, Y.,
Buzsaki, G.,
Diamond, D.M., Frackowiak, R.,
Giedd, J.,
Girault, J.A., Grace, A.A., Lambert, J.J., Manji, H., Mayberg, H.,
Popoli, M., Prochiantz, A., Richter-Levin, G., Somogyi, P., Spedding,
M., Svenningsson, P. and Weinberger, D. (2007) How can drug discovery
for psychiatric disorders be improved? Nature Reviews/Drug Discovery 6:
189-201.
- Laviolette, S.R.
and
Grace, A.A. (2006) The roles of cannabinoid and
dopamine receptor systems in neural emotional learning circuits:
Implications for schizophrenia and addiction. Cellular and Molecular
Life Sciences 63: 1597-1613.
- Grace, A.A.
(2007)
Stress-induced pathophysiology within the
schizophrenia patient brain: A model for the delayed onset of psychosis
and its circumvention by anxiolytic agents. Adolescent Brain and
Psychopathology: Integrating Brain and Prevention Science. Ed. D. Romer
& E.F. Walker. Oxford University Press, pp. 245-263.
- Goto, Y. and
Grace,
A.A. (2007) The dopamine system and the
pathophysiology of schizophrenia: A basic science perspective. In:
Integrating the Neurobiology of Schizophrenia. Ed: A. Abi-Dargham
& O. Guillin. International Review of Neurobiology 78: 42-58.
- Belujon, P.,
Lodge,
D.J. and Grace, A.A. (2007) Dopamine systems in
Parkinson’s disease and L-DOPA induced dyskinesias
– what goes wrong? US Neurological Disease 2007, Volume II
56-58.
- Lodge, D.J. and
Grace,
A.A. (2008) Hippocampal dysfunction and
disruption of dopamine system regulation in an animal model of
schizophrenia. Neurotoxicity Research 14: 97-104.
- Lodge, D.J.,
Buffalari,
D.M. and Grace, A.A. (2009) Dopamine: CNS
pathways and neurophysiology. In: Encyclopedia of Neuroscience. Ed:
L.R. Squire, pp. 549-555.
- Heinz, A., Beck,
A.,
Grusser, S.M., Grace, A.A. and Wrase, J. (2009)
Identifying the neuronal circuitry of alcohol craving and relapse
vulnerability. Addiction Biology 14: 108-118.
- Heinz, A., Grace,
A.A.
and Beck, A. (2009) The intricacies of dopamine
neuron modulation. Biological Psychiatry 65: 101-102.
- Grace, A.A.,
Rosenkranz, J.A. and West, A.R. (2009) Electrophysiology.
In: American Psychiatric Press Textbook of Psychopharmacology, Fourth
Edition. Ed. C.B. Nemeroff and A.F. Schatzberg, American Psychiatric
Press, Washington, D.C. pp. 135-151.
- Lodge, D.J. and
Grace,
A.A. (2009) Gestational methylazoxymethanol
acetate administration: a developmental disruption model of
schizophrenia. Behavioral Brain Research 204:306-12.
- Grace, A.A.
(2009)
Animal models of schizophrenia: Focus on hippocampal
disruption of dopamine system regulation. In: Advances in Schizophrenia
Research 2009. Eds. W.F. Gattaz, & G. Busatto, Springer-Verlag
pp. 175-191.
- Grace, A.A.
(2009) DA
modulation of forebrain pathways and the
pathophysiology of psychiatric disorders. Dopamine Handbook. Ed. A.
Bjorklund, L. Iversen, and S. Iversen. Oxford University Press, pp.
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