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Original Articles
  1. Bunney, B.S.and Grace, A.A.(1978) Acute and chronic haloperidol treatment: Comparison of effects on nigral dopaminergic cell activity. Life Sci. 23:1715-1728.

  2. Skirboll, L.R., Grace, A.A.and Bunney, B.S.(1979) Dopamine auto- and postsynaptic receptors: Electrophysiological evidence for differe­ntial sensitivity to dopamine agonists. Science 206:80-8­2.

  3. Grace, A.A.and Bunney, B.S.(1979) Paradoxical GABA excitation of nigral dopaminergic cells: Indirect mediation through reticulata inhibitory neurons. Eur. J. Pharmacol. 59:211-218.

  4. Grace, A.A.and Bunney, B.S.(1980) Effects of baclofen on nigral dopaminergic cell activity following acute and chronic haloperidol treatment. Brain Res. Bull. 5 (Suppl.2):537-543.

  5. Grace, A.A., Hommer, D.W.and Bunney, B.S.(1980) Peripheral and striatal influences on nigral dopamine cells: Mediation by reticulata neurons. Brain Res. Bull. 5 (Suppl.2):105-109.

  6. Bannon, M.J., Grace, A.A., Bunney, B.S.and Roth, R.H.(1980) Evidence for an irreversible interaction of bromocryptine with central dopamine receptors. Naunyn-Schmiedeberg's Arch. Pharmaco­l. 312:37-41.

  7. Grace, A.A.and Bunney, B.S.(1980) Nigral dopamine neurons: Intracellular recording and identification using L-DOPA injection combined with fluorescence histochemistry. Science 210:654-656.

  8. Skirboll, L.R., Grace, A.A., Hommer, D.W., Rehfeld, J., Goldstein, M., Hökfelt, T.and Bunney, B.S.(1981) Peptide-monoamine coexis­tence: Studies of the actions of cholecystokinin-like peptide on the elec­trical activity of midbrain dopamine neurons. Neur­oscience 6:2111-2124.

  9. Grace, A.A.and Bunney, B.S.(1983) Intracellular and extracellular electrophysiology of nigral dopaminergic neurons.I.Identifi­cation and characterization. Neuroscience 10:301-315.

  10. Grace, A.A.and Bunney, B.S.(1983) Intracellular and extracellular electrophysiology of nigral dopaminergic neurons.II.Action potential generating mechanisms and morphological correlates. Neuroscience 10:317-331.

  11. Grace, A.A.and Bunney, B.S.(1983) Intracellular and extracellular electrophysiology of nigral dopaminergic neurons.III.Evidence for electrical coupling. Neuroscience 10:333-348.

  12. Grace, A.A.(1983) Nigral dopamine neurons: Identification, characterization, and effects of autoreceptor stimulation. Yale University dissertation.

  13. Chiodo, L.A., Bannon, M.J., Grace, A.A., Roth, R.H.and Bunney, B.S.(1984) Absence of autoreceptors on a subpopulation of mesocortical dopamine neurons: Electrophysiological and biochem­ical evidence. Neuroscience 12:1-16.

  14. Grace, A.A.and Bunney, B.S.(1984) The control of firing pattern in nigral dopamine neurons: Single spike firing. J. Neuroscience 4:2866-2876.

  15. Grace, A.A.and Bunney, B.S.(1984) The control of firing pattern in nigral dopamine neurons: Burst firing. J. Neuroscience 4:2877-­2890.

  16. Grace, A.A.and Bunney, B.S.(1985) Opposing effects of striato­nigral feedback pathways on midbrain dopamine cell activity. Brain Res. 333:271-284.

  17. Grace, A.A.and Bunney, B.S.(1985) Low doses of apomorphine elicit two opposing influences on dopamine cell electrophysiology. Brain Res. 333:285-298.

  18. Grace, A.A.and Llinás, R.(1985) Morphological artifacts induced in intracellularly stained neurons by dehydration: Circumvention using rapid dimethyl sulfoxide clearing. ­Neuroscience 16:461-475.

  19. Grace, A.A. and Bunney, B.S. (1986) Induction of depolarization block in midbrain dopamine neurons by repeated administration of haloper­idol: Analysis using in vivo intracellular recording. J. Pharmacol. Exp. Therapeut. 238: 1092-1100.

  20. Hollerman, J.R. and Grace, A.A. (1989) Acute haloperidol administration induces depolarization block of nigral dopamine neurons in rats after partial dopamine lesions. Neuroscience Letters 96: 82-88.

  21. Grace, A.A. and Onn, S.-P. (1989) Morphology and electrophysiological properties of immunocytochemically identified rat dopamine neurons recorded in vitro. J. Neuroscience 9: 3463-3481.

  22. Zigmond, M.J., Berger, T.W., Grace, A.A. and Stricker, E.M. (1989) Compensatory responses to nigrostriatal bundle injury: Studies with 6-hydroxydopamine in an animal model of Parkinsonism. Molecular and Chemical Neuropathology 10: 185-200.

  23. Grace, A.A. (1990) Evidence for the functional compartmentalization of spike generating regions of rat midbrain dopamine neurons recorded in vitro. Brain Res. 524: 31-41.

  24. Hollerman, J.R. and Grace, A.A. (1990) The effects of dopamine-depleting brain lesions on the electrophysiological activity of rat substantia nigra dopamine neurons. Brain Research 533: 203-212.

  25. Zigmond, M.J., Abercrombie, E.D., Berger, T.W., Grace, A.A. and Stricker, E.M. (1990) Compensations to nigrostriatal bundle injury: Some clinical and basic implications. Trends in Neuroscience 13: 290-296.

  26. Grace, A.A. (1991) Phasic versus tonic dopamine release and the modulation of dopamine system responsivity: A hypothesis for the etiology of schizophrenia. Neuroscience 41: 1-24.

  27. Grace, A.A. (1991) Regulation of spontaneous activity and oscillatory spike firing in rat midbrain dopamine neurons recorded in vitro. Synapse 7: 221-234.

  28. Llinás, R., Grace, A.A. and Yarom, Y. (1991) In vitro neurons in mammalian cortical layer 4 exhibit intrinsic oscillatory activity in the 10 to 50 Hz frequency. Proc. Natl. Acad. Sci. USA 88: 897-901.

  29. Bunney, B.S., Chiodo, L.A. and Grace, A.A. (1991) Midbrain dopamine system electrophysiological functioning: A review and a new hypothesis. Synapse 9: 79-94.

  30. Pucak, M.L. and Grace, A.A. (1991) Partial dopamine depletions result in an enhanced sensitivity of residual dopamine neurons to apomorphine. Synapse 9: 144-155.

  31. Hollerman, J.R., Abercrombie, E.D. and Grace, A.A. (1992) Electrophysiological, biochemical, and behavioral studies of acute haloperidol-induced depolarization block of nigral dopamine neurons. Neuroscience 47: 589-601.

  32. Nisenbaum, E.S., Grace, A.A. and Berger, T.W. (1992) Functionally distinct subpopulations of striatal neurons are differentially regulated by GABAergic and dopaminergic inputs. II. in vitro analysis. Neuroscience 48: 579-593.

  33. Nisenbaum, E.S., Berger, T.W. and Grace, A.A. (1992) Presynaptic modulation by GABAB receptors of glutamatergic excitation and GABAergic inhibition of neostriatal neurons. J. Neurophysiol. 67: 477-481.

  34. Hollerman, J.R. and Grace, A.A. (1992) Subthalamic nucleus cell firing in the 6-OHDA-treated rat: Basal activity and response to haloperidol. Brain Res. 590: 291-299.

  35. Smith, I.D. and Grace, A.A. (1992) Role of the subthalamic nucleus in the regulation of nigral dopamine neuron activity. Synapse 12: 287-303.

  36. Grace, A.A. (1992) The depolarization block hypothesis of neuroleptic action: Implications for the etiology and treatment of schizophrenia. J. Neural Transm. 36 (suppl.): 91-131.

  37. O'Donnell, P. and Grace, A.A. (1993) Physiological and morphological properties of accumbens core and shell neurons recorded in vitro. Synapse 13: 135-160.

  38. Nisenbaum, E.S., Berger, T.W. and Grace, A.A. (1993) Depression of glutamatergic and GABAergic synaptic responses in striatal spiny neurons by stimulation of presynaptic GABAB receptors. Synapse 14: 221-242.

  39. Grace, A.A. (1993) Cortical regulation of subcortical dopamine systems and its possible relevance to schizophrenia. J. Neural Transm. 91: 111-134.

  40. O'Donnell, P. and Grace, A.A. (1993) Dopaminergic modulation of dye coupling between neurons in the core and shell regions of the nucleus accumbens. Journal of Neuroscience 13: 3456-3471.

  41. Onn, S.-P., Berger, T.W. and Grace, A.A. (1994) Identification and characterization of striatal cell subtypes using in vivo intracellular recording in rats: I. Basic physiology and response to corticostriatal fiber stimulation. Synapse 16: 161-180.

  42. Onn, S.-P., Berger, T.W. and Grace, A.A. (1994) Identification and characterization of striatal cell subtypes using in vivo intracellular recording in rats: II. Membrane factors underlying paired pulse response profiles. Synapse 16: 195-210.

  43. Onn, S.-P., Berger, T.W. and Grace, A.A. (1994) Identification and characterization of striatal cell subtypes using in vivo intracellular recording and dye-labeling in rats: III. Morphological correlates and compartmental localization. Synapse 16: 231-254.

  44. O'Donnell, P. and Grace, A.A. (1994) Tonic D2-mediated attenuation of cortical excitation in nucleus accumbens neurons recorded in vitro. Brain Research 634: 105-112.

  45. Onn, S.-P. and Grace, A.A. (1994) Dye coupling between rat striatal neurons recorded in vivo: Compartmental organization and modulation by dopamine. Journal of Neurophysiology 71: 1917-1934.

  46. Lavin, A. and Grace, A.A. (1994) The modulation of dorsal thalamic cell activity by the ventral pallidum: Its role in the regulation of thalamocortical activity by the basal ganglia. Synapse 18: 104-127.

  47. Pucak, M.L. and Grace, A.A. (1994) Evidence that systemically administered dopamine antagonists activate dopamine neuron firing primarily by blockade of somatodendritic autoreceptors. Journal of Pharmacology and Experimental Therapeutics 371: 1181-1192.

  48. Grace, A.A. (1995) The tonic/phasic model of dopamine system regulation: Its relevance for understanding how stimulant abuse can alter basal ganglia function. Drug and Alcohol Dependence 37: 111-129.

  49. O'Donnell, P. and Grace, A.A. (1995) Synaptic interactions among excitatory afferents to nucleus accumbens neurons: Hippocampal gating of prefrontal cortical input. Journal of Neuroscience 15: 3622-3639.

  50. O'Donnell, P. and Grace, A.A. (1995) Differential effects of subchronic clozapine and haloperidol on dye coupling between neurons in the rat striatal complex. Neuroscience 66: 763-767.

  51. Harden, D.G. and Grace, A.A. (1995) Activation of dopamine cell firing by repeated L-DOPA administration to dopamine-depleted rats: Its potential role in mediating the therapeutic response to L-DOPA treatment. Journal of Neuroscience 15: 6157-6166.

  52. Onn, S.-P. and Grace, A.A. (1995) Repeated treatment with haloperidol and clozapine exerts differential effects on dye coupling between neurons in subregions of striatum and nucleus accumbens. Journal of Neuroscience 15: 7024-7036.

  53. Lavin, A. and Grace, A.A. (1996) Physiological properties of ventral pallidal neurons recorded intracellularly in vivo. Journal of Neurophysiology 75: 1432-1443.

  54. Pucak, M.L. and Grace, A.A. (1996) Effects of haloperidol on the activity and membrane physiology of substantia nigra dopamine neurons recorded in vitro. Brain Research 713: 44-52.

  55. O’Donnell, P. and Grace, A.A. (1996) Dopaminergic reduction of excitability in nucleus accumbens neurons recorded in vitro. Neuropsychopharmacology 15: 87-97.

  56. Grace, A.A., Bunney, B.S., Moore, H. And Todd, C.L. (1997) Dopamine cell depolarization block as a model for the therapeutic actions of antipsychotic drugs. Trends in Neuroscience 20: 31-37.

  57. O’Donnell, P. and Grace, A.A. (1997) Cortical afferents modulate striatal gap junction permeability via nitric oxide. Neuroscience 76: 1-5.

  58. O’Donnell, P., Lavin, A., Enquist, L.W., Grace, A.A. and Card, J.P. (1997) Interconnected parallel circuits between rat nucleus accumbens and thalamus revealed by retrograde transynaptic transport of pseudorabies virus. Journal of Neuroscience 17: 2143-2167.

  59. Mana, M.J. and Grace, A.A. (1997) Chronic cold stress alters the basal and evoked electrophysiological activity of rat locus coeruleus neurons. Neuroscience 81: 1055-1064.

  60. Lavin, A. and Grace, A.A. (1998) Response of the ventral pallidal/mediodorsal thalamic system to antipsychotic drug administration: Involvement of the prefrontal cortex. Neuropsychopharmacology 18: 352-363.

  61. O’Donnell, P. and Grace, A.A. (1998) Dysfunctions in multiple interrelated systems as the neurobiological bases of schizophrenic symptom clusters. Schizophrenia Bulletin 24: 267-283.

  62. Grace, A.A. and Moore, H. (1998) Regulation of information flow in the nucleus accumbens: A model for the pathophysiology of schizophrenia. In: Origins and development of schizophrenia: Advances in experimental psychopathology." Ed. M.F. Lenzenweger and R.H. Dworkin, American Psychological Association Press, Washington, DC pp. 123-157.

  63. Harden, D.G., King, D., Finlay, J. and Grace, A.A. (1998) Depletion of dopamine in the prefrontal cortex decreases the basal electrophysiological activity of mesolimbic dopamine neurons. Brain Research 794: 96-102.

  64. O’Donnell, P. and Grace, A.A. (1998) Phencyclidine interferes with the hippocampal gating of nucleus accumbens neuronal activity in vivo. Neuroscience 87: 823-830.

  65. Fienberg, A.A., Hiroi, N., Mermelstein, P., Song, W.-J., Snyder, G.L., Nishi, A., Cheramy, A., O’Callaghen, J.P., Miller, D., Cole, D.G., Corbett, R., Haile, C.N., Cooper, D.C., Onn, S.-P., Grace, A.A., Ouimet, C.C., White, F.J., Hyman, S.E., Surmeier, D.J., Girault, J.A., Nestler, E.J. and Greengard, P. (1998) DARPP-32, regulator of the efficacy of dopaminergic transmission Science 281: 838-842.

  66. Moore, H., Todd, C.L, and Grace, A.A. (1998) Striatal extracellular dopamine levels in rats with haloperidol-induced depolarization block of substantia nigra dopamine neurons. Journal of Neuroscience 18: 5068-5077.

  67. Lavin, A. and Grace, A.A. (1998) Dopamine modulates the responsivity of mediodorsal thalamic cells recorded in vitro. Journal of Neuroscience 18: 10566-10578.

  68. Todd, C.L. and Grace, A.A. (1999) Interaction of benztropine and haloperidol actions on rat substantia nigra dopamine cell electrophysiological activity in vivo. Brain Research Bulletin 48: 219-222.

  69. Onn, S.-P. and Grace, A.A. (1999) Alterations in electrophysiological activity and dye coupling of striatal spiny and aspiny neurons in dopamine-denervated rat striatum recorded in vivo. Synapse 33: 1-15.

  70. Newman, J. and Grace, A.A. (1999) Binding across time: the selective gating of frontal and hippocampal systems modulating working memory and attentional states. Consciousness and Cognition 8: 196-212.

  71. Rosenkranz, J.A. and Grace, A.A. (1999) Modulation of basolateral amygdala neuronal firing and afferent drive by dopamine receptor activation in vivo. Journal of Neuroscience 19: 11027-11039.

  72. Grace, A.A. (2000) The tonic/phasic model of dopamine system regulation and its implications for understanding alcohol and psychostimulant craving. Addiction 95 (Supplement 2): S119-128.

  73. West, A.R. and Grace, A.A. (2000) Striatal nitric oxide signaling regulates the neuronal activity of midbrain dopamine neurons in vivo. Journal of Neurophysiology 83: 1796-1808.

  74. Onn, S.-P. and Grace, A.A. (2000) Amphetamine withdrawal alters bistable states and cellular coupling in rat prefrontal cortex and nucleus accumbens neurons recorded in vivo. Journal of Neuroscience 20: 2332-2345.

  75. Onn, S.P., West, A.R. and Grace, A.A. (2000) Dopamine mediated regulation of striatal neuronal and network interactions. Trends in Neurosciences 23 (supplement) S48-S56.

  76. Moore, H., Rose, H.J.. and Grace, A.A. (2001) Chronic cold stress reduces the spontaneous activity of ventral tegmental dopamine neurons. Neuropsychopharmacology 24: 410-419.

  77. Drevets, W.C., Gautier, C., Price, J.C., Kupfer, D.J., Kinahan, P.E., Grace, A.A., Price, J.L, and Mathis, C. (2001) Amphetamine-induced dopamine release in human ventral striatum correlates with euphoria. Biological Psychiatry 49: 81-96.

  78. Lavin, A. and Grace, A.A. (2001) Stimulation of D1-type dopamine receptors enhances excitation in prefrontal cortical pyramidal neurons in a state-dependent manner. Neuroscience 104: 335-346.

  79. Turner, M.S., Lavin, A., Grace, A.A. and Napier, T.C. (2001) Regulation of limbic information outflow by the subthalamic nucleus: Excitatory amino acid projections to the ventral pallidum. Journal of Neuroscience 21: 2820-2832.

  80. Jedema, J.P., Finlay, J.M., Sved, A.F. and Grace, A.A. (2001) Chronic cold exposure potentiates corticotropin releasing hormone (CRH)-evoked increases in electrophysiological activity of locus coeruleus neurons. Biological Psychiatry 49: 351-359.

  81. Floresco, S.B., Todd, C.L. and Grace, A.A. (2001) Glutamatergic afferents from the hippocampus to the nucleus accumbens regulate activity of ventral tegmental area dopamine neurons. Journal of Neuroscience 21: 4915-4922.

  82. Rosenkranz, J.A. and Grace, A.A. (2001) Dopamine attenuates prefrontal cortical suppression of sensory inputs to the basolateral amygdala of rats. Journal of Neuroscience 21: 4090-4103.

  83. West, A.R. and Grace, A.A. (2002) Opposite Influences of endogenous dopamine D1 and D2 receptor activation on activity states and electrophysiological properties of striatal neurons: Studies combining in vivo intracellular recordings and reverse microdialysis. Journal of Neuroscience 22: 294-304.

  84. Rosenkranz, J.A. and Grace, A.A. (2002) Cellular mechanisms of infralimbic and prelimbic prefrontal cortical inhibition and dopaminergic modulation of basolateral amygdala neurons in vivo. Journal of Neuroscience 22: 324-337.

  85. West, A.R., Galloway, M.P. and Grace, A.A. (2002) Regulation of striatal dopamine neurotransmission by nitric oxide: Effector pathways and signaling mechanisms. Synapse 44: 227-245.

  86. Rosenkranz, J.A. and Grace, A.A. (2002) Dopamine-mediated modulation of odour-evoked amygdala potentials during Pavlovian conditioning. Nature 417: 282-287.

  87. West, A.R., Moore, H. and Grace, A.A. (2002) Direct examination of local regulation of membrane activity in striatal and prefrontal cortical neurons in vivo using simultaneous intracellular recording and microdialysis. Journal of Pharmacology and Experimental Therapeutics 301: 867-877

  88. Singer, H.S., Szymanski, S., Giuliano, J., Yokoi, F., Dogan, A.S., Brasic, J.R., Grace, A.A. and Wong, D.F. (2002) Elevated intrasynaptic dopamine release in Tourette Syndrome measured by PET. American Journal of Psychiatry 159: 1329-1336.

  89. Moore, H. and Grace, A.A. (2002) A role for electrotonic coupling in the striatum in the expression of dopamine receptor-mediated stereotypies. Neuropsychopharmacology 27: 980-992.

  90. Rosenkranz, J.A. and Grace, A.A. (2002) Response: Mechanisms of pavlovian fear conditioning. Trends in Neurosciences 25: 437-438.

  91. Jedema, H.P. and Grace, A.A. (2003) Chronic exposure to cold stress alters electrophysiological properties of locus coeruleus neurons recorded in vitro. Neuropsychopharmacology 28:63-72.

  92. Floresco, S.B. and Grace, A.A. (2003) Gating of hippocampal-evoked activity in prefrontal cortical neurons by inputs from the mediodorsal thalamus and ventral tegmental area. Journal of Neuroscience 23: 3930-3943.

  93. Onn, S.-P., Fienberg, A.A., and Grace, A.A. (2003) Dopamine modulation of membrane excitability in striatal spiny neurons is altered in DARPP-32 knockout mice. Journal of Pharmacology and Experimental Therapeutics 306: 870-879.

  94. Charara, A. and Grace, A.A. (2003) Dopamine receptor subtypes selectively modulate excitatory afferents from the hippocampus and amygdala to rat nucleus accumbens neurons. Neuropsychopharmacology 28: 1412-1421.

  95. Floresco, S.B., West, A.R., Ash, B., Moore, H. and Grace, A.A. (2003) Afferent modulation of dopamine neuron firing differentially regulates tonic and phasic dopamine transmission. Nature Neuroscience 6: 968-973.

  96. Rosenkranz, J.A., Moore, H. And Grace, A.A. (2003) The prefrontal cortex regulates lateral amygdala neuronal plasticity and response to previously conditioned stimuli. Journal of Neuroscience 23: 11054-11064.

  97. Grace, A.A. (2003) Gating within limbic-cortical circuits and its alteration in a developmental disruption model of schizophrenia. Clinical Neuroscience Research 3: 333-338.

  98. West, A.R. and Grace, A.A. (2004) The nitric oxide-guanylyl cyclase signaling pathway modulates membrane activity states and electrophysiological properties of striatal medium spiny neurons recorded in vivo. Journal of Neuroscience 24: 1924 - 1935.

  99. Floresco, S.B., West, A.R. and Grace, A.A. (2004) Extrasynaptic dopamine and phasic neuronal activity. Reply. Nature Neuroscience 7: 199.

  100. Thompson, J.L., Pogue-Geile, M.F. and Grace, A.A. (2004) Developmental pathology, dopamine, and stress: A model for the age of onset of schizophrenia symptoms. Schizophrenia Bulletin 30: 875-900.

  101. Fiore, M., Grace, A.A., Korf, J., Stampachiacchiere, B. And Aloe, L. (2004) Impaired brain development in the rat following prenatal exposure to methylazoxymethanol acetate at gestational day 17 and neurotrophin distribution. NeuroReport 15: 1791-1795.

  102. Bilder, R.M., Volavka, J., Lachman, H.M. and Grace, A.A. (2004) The catechol-O-methyltransferase polymorphism: Relations to the tonic-phasic dopamine hypothesis and neurocognitive phenotypes. Neuropsychopharmacology 29: 1943-1961.

  103. Jedema, H.P. and Grace, A.A. (2004) Corticotropin-releasing hormone directly activates noradrenergic neurons of the locus coeruleus recorded in vitro. Journal of Neuroscience 24: 9703-9713.

  104. Kroner, S., Rosenkranz, J.A., Grace, A.A. and Barrionuevo, G. (2005) Dopamine modulates excitability of basolateral amygdala neurons in vitro. Journal of Neurophysiology 93: 1598-1610.

  105. Lodge, D.L. and Grace, A.A. (2005) Acute and chronic Corticotropin Releasing Factor 1 receptor blockade inhibits cocaine-induced dopamine release: Correlation with dopamine neuron activity. Journal of Pharmacology and Experimental Therapeutics 314: 201-206

  106. Lavin, A., Moore, H., and Grace, A.A. (2005) Prenatal disruption of neocortical development alters prefrontal cortical neuron responses to dopamine in adult rat. Neuropsychopharmacology 30, 1426-1435.

  107. Goto, Y. and Grace, A.A. (2005) Dopaminergic modulation of limbic and cortical drive of nucleus accumbens in goal-directed behavior. Nature-Neuroscience 8: 805-812.

  108. Correll, C.M., Rosenkranz, J.A. and Grace, A.A. (2005) Chronic cold stress alters prefrontal cortical modulation of amygdala neuronal activity in rats. Biological Psychiatry 58: 382-391.

  109. Lisman, J. and Grace, A.A. (2005) The hippocampal-VTA loop: control of entry into long-term memory. Neuron 46: 703-713.

  110. Laviolette, S.R., Lipski W.J. and Grace, A.A. (2005) A subpopulation of neurons in the medial prefrontal cortex encode emotional learning with burst and frequency codes through a dopamine D4 receptor-dependent basolateral amygdala input. Journal of Neuroscience 25: 6066-6075.

  111. Goto, Y. and Grace, A.A. (2005) Dopamine-dependent interactions between limbic and prefrontal cortical synaptic plasticity in the nucleus accumbens: Disruption by cocaine sensitization. Neuron 47: 255-266.

  112. Floresco, S.B., Geyer, M.A., Gold, L.H., and Grace, A.A. (2005) Developing predictive models and establishing a preclinical trials network for assessing treatment effects on cognition in animals. Schizophrenia Bulletin 31: 888-894.

  113. Onn, S.-P., Wang, X.-B., Lin M. and Grace, A.A. (2006) Dopamine D1 and D4 receptors differentially modulate recurrent excitatory synapses in prefrontal cortical pyramidal neurons. Neuropsychopharmacology 31: 318-338.

  114. Miner, L.H., Jedema, H.P., Moore, F.W., Blakely, R.D., Grace, A.A. and Sesack, S.R. (2006) Chronic stress increases the plasmalemmal distribution of the norepinephrine transporter and the co-expression of tyrosine hydroxylase in norepinephrine axons in the prefrontal cortex. Journal of Neuroscience 26: 1571-1578.

  115. Lodge, D.J. and Grace, A.A. (2006) The laterodorsal tegmental nucleus is essential for burst firing of dopamine neurons in the rat VTA. Proceedings of the National Academy of Sciences, USA 1003 (13) 5167-5172.

  116. Rosenkranz, J.A., Buffalari, D.M. and Grace, A.A. (2006) Opposing influence of basolateral amygdala and footshock stimulation on neurons of the central amygdala. Biological Psychiatry 59: 801-811.

  117. Laviolette, S.R. and Grace, A.A. (2006) Cannabinoids dramatically potentiate neuronal emotional learning in the medial prefrontal cortex through basolateral amygdala inputs Journal of Neuroscience 26: 6458-6468.

  118. Lodge, D.J. and Grace, A.A. (2006) The hippocampus modulates dopamine neuron responsivity by regulating the intensity of phasic neuron activation. Neuropsychopharmacology 31: 1356-1361.

  119. Moore, H., Ghajarnia, M.E., Jentsch, J.D., Geyer, M.A. and Grace, A.A. (2006) A Neurobehavioral Systems Analysis of Adult Rats Exposed to Methylazoxymethanol Acetate on E17: Implications for the Neuropathology of Schizophrenia. Biological Psychiatry 60: 253-264.

  120. Goto, Y. and Grace, A.A. (2006) Alterations in prefrontal cortical activity and plasticity in adult rats with disruption of cortical development. Biological Psychiatry 60: 1259-1267.

  121. Kawashima, H., Izaki, Y., Grace, A.A., and Takita, M. (2006) Cooperativity between hippocampal-prefrontal short-term plasticity through associative long-term potentiation. Brain Research 1109: 37-44.

  122. Wong, D.F., Kuwabara, H., Schretlin, D., Bonson, K., Zhou, Y., Nandi, A., Brasic, J., Kimes, A.S., Maris M.A., Kumar, A., Contoreggi, C., Links, J., Ernst, M., Rousset, O., Zukin, S., Grace, A.A., Rohde, C., Jasinski, D.R., Gjedde, A. and London, E.D. (2006) Increased occupancy of dopamine receptors in human striatum during cue-elicited cocaine craving. Neuropsychopharmacology 31: 2716-2727.

  123. Grace, A.A., Floresco, S.B., Goto, Y. and Lodge, D.J. (2007) The regulation of dopamine neuron firing and the control of goal-directed behaviors. Trends in Neurosciences 30:220-227.

  124. Lodge, D.J. and Grace, A.A. (2007) Aberrant hippocampal activity underlies the dopamine dysregulation in an animal model of schizophrenia. Journal of Neuroscience 27: 11424-11430.

  125. Goto, Y. and Grace, A.A. (2007) The Yin and Yang of Dopamine Release: A New Perspective. Neuropharmacology 53: 583-587.

  126. Buffalari, D.M. and Grace, A.A. (2007) Noradrenergic modulation of basolateral amygdala neuronal activity: Opposing influences of alpha-2 and beta receptor activation. Journal of Neuroscience 27: 12358-12366.

  127. McCracken, C.B. and Grace, A.A. (2007) High-frequency deep brain stimulation of the nucleus accumbens region suppresses neuronal activity and selectively modulates afferent drive in rat orbitofrontal cortex in vitro. Journal of Neuroscience 27: 12601-12610.

  128. Bissière, S., Plachta, N., McAllister, K.H., Hoyer, D., Olpe, H.-R., Grace, A.A. and Cryan, J.F. (2008) The rostral anterior cingulate cortex modulates the efficiency of amygdala-dependent fear learning. Biological Psychiatry 63: 821-831.

  129. Onn, S.-P., Lin, M., Liu, J. and Grace, A.A. (2008) Dopamine DARPP-32-dependent modulation of prefrontal cortical input and intercellular coupling in mouse accumbens spiny and aspiny neurons. Neuroscience 151: 802-816.

  130. Wong, D.F., Brasic, J., Singer, H., Schretlen, D., Kuwabara, H., Zhou, Y., Nandi, A., Maris, M., Alexander, M., Ye, W., Rousset, O., Kumar, A., Szabo, Z., Gjedde, A. and Grace, A.A. (2008) Mechanisms of dopamine and serotonin in Tourette syndrome: Clues from an in vivo neurochemistry study with PET. Neuropsychopharmacology 33: 1239-1251.

  131. Lisman, J.E., Coyle, J.T., Greene, R.W., Javitt, D.C., Benes, F.M., Heckers, S. and Grace, A.A. (2008) Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia Trends in Neurosciences 31: 234-242.

  132. Jedema, H.P..P, Gold, S.J., Gonzalez-Burgos, G., Sved, A.F., Tobe, B.J., Wensel, T.G. and Grace, A.A. (2008) Chronic cold exposure increases RGS7 expression and decreases ?2-autoreceptor-mediated inhibition of noradrenergic locus coeruleus neurons. European Journal of Neuroscience 27: 2433-2443.

  133. Krystal JH, Carter CS, Geschwind D, Manji HK, March JS, Nestler EJ, Zubieta JK, Charney DS, Goldman D, Gur RE, Lieberman JA, Roy-Byrne P, Rubinow DR, Anderson SA, Barondes S, Berman KF, Blair J, Braff DL, Brown ES, Calabrese JR, Carlezon WA Jr, Cook EH Jr, Davidson RJ, Davis M, Desimone R, Drevets WC, Duman RS, Essock SM, Faraone SV, Freedman R, Friston KJ, Gelernter J, Geller B, Gill M, Gould E, Grace AA, Grillon C, Gueorguieva R, Hariri AR, Innis RB, Jones EG, Kleinman JE, Koob GF, Krystal AD, Leibenluft E, Levinson DF, Levitt PR, Lewis DA, Liberzon I, Lipska BK, Marder SR, Markou A, Mason GF, McDougle CJ, McEwen BS, McMahon FJ, Meaney MJ, Meltzer HY, Merikangas KR, Meyer-Lindenberg A, Mirnics K, Monteggia LM, Neumeister A, O'Brien CP, Owen MJ, Pine DS, Rapoport JL, Rauch SL, Robbins TW, Rosenbaum JF, Rosenberg DR, Ross CA, Rush AJ, Sackeim HA, Sanacora G, Schatzberg AF, Shaham Y, Siever LJ, Sunderland T, Tecott LH, Thase ME, Todd RD, Weissman MM, Yehuda R, Yoshikawa T, Young EA, McCandless R (2008) It is time to take a stand for medical research and against terrorism targeting medical scientists. Biological Psychiatry 63: 725-727

  134. Goto, Y. and Grace, A.A. (2008) Dopamine modulation of hippocampal-prefrontal cortical interaction drives memory-guided behavior. Cerebral Cortex 18: 1407 - 1414.

  135. McGinty, V.B. and Grace, A.A. (2008) Selective activation of medial prefrontal-to-accumbens projection neurons by amygdala stimulation and pavlovian conditioned stimuli. Cerebral Cortex 18: 1961-1972

  136. Lodge, D.J. and Grace, A.A. (2008) Augmented hippocampal drive of mesolimbic dopamine neurons: A mechanism of psychostimulant sensitization. Journal of Neuroscience 28 7876-7882.

  137. Grace, A.A. (2008) Physiology of the normal and dopamine-depleted basal ganglia: Insights into L-DOPA pharmacotherapy. Movement Disorders 25S3: S560-S569.

  138. Belujon, P. and Grace, A.A. (2008) Critical role of the prefrontal cortex in the regulation of hippocampus-accumbens information flow. Journal of Neuroscience 28: 9797-9805.

  139. Goto, Y, and Grace, A.A. (2008) Limbic and cortical information processing in the nucleus accumbens. Trends in Neurosciences 31: 552-558.

  140. Sengupta, S.M., Grizenko, N., Schmitz, N., Schwartz, G., Bellingham, J., Polotskaia, A., Ter Stepanian, M., Goto, Y., Grace, A.A. and Joober, R. (2008) COMT Val 108/158Met polymorphism modulates task-oriented behaviour in children with ADHD Neuropsychopharmacology 33: 3069-3077.

  141. Buffalari, D.M. and Grace, A.A. (2009) Chronic cold stress increases excitatory effects of norepinephrine on spontaneous and evoked activity of basolateral amygdala neurons. International Journal of Neuropsychopharmacology 12: 95-107.

  142. Valenti, O. and Grace, A.A. (2009) Entorhinal cortex modulates the activity states of electrophysiologically characterized medial prefrontal cortical neurons. Cerebral Cortex 19: 658-674.

  143. Lodge, D.J., Behrens, M.M. and Grace, A.A. (2009) A loss of parvalbumin-containing interneurons is associated with diminished oscillatory activity in an animal model of schizophrenia. Journal of Neuroscience 29:2344-2354.

  144. McGinty, V.B. and Grace, A.A. (2009) Timing-dependent regulation of evoked spiking in nucleus accumbens neurons by integration of limbic and prefrontal cortical inputs. Journal of Neurophysiology 101: 1823-1835.

  145. McCracken, C.B. and Grace, A.A. (2009) Nucleus accumbens deep brain stimulation produces region-specific alterations in local field potential oscillations and evoked responses in vivo. Journal of Neuroscience 29: 5354-5363.

  146. McGinty, V.B. and Grace, A.A. (2009) Activity-dependent depression of medial prefrontal cortex inputs to accumbens neurons by the basolateral amygdala. Neuroscience 162: 1429-1436.

  147. Buffalari, D.M. and Grace, A.A. (2009) Anxiogenic modulation of spontaneous and evoked neuronal activity in the basolateral amygdala. Neuroscience 163: 1069-1077.

  148. Kumra, S. Asarnow, R., Grace, A.A., Keshavan, M., McClellan, J., Sikich, L. and Wagner, A. (2009) From bench to bedside: Translating new research from neuroimaging and genetics into treatment development for early-onset schizophrenia. Early Intervention in Psychiatry 3(4) 178-188.

  149. Valenti, O. and Grace, A.A. (2010) Antipsychotic drug-induced increases in ventral tegmental area dopamine neuron population activity via activation of the nucleus accumbens-ventral pallidal pathway. International Journal of Neuropsychopharmacology 13(7): 845-60.

  150. Grace, A.A. (2010) Ventral hippocampus, interneurons and schizophrenia: A new understanding of the pathophysiology of schizophrenia and its implications for treatment and prevention. Current Directions in Psychological Science 19: 232-237.

  151. Belujon, P., Lodge, D.J. and Grace, A.A. (2010) Aberrant striatal plasticity is specifically associated with dyskinesias following L-DOPA treatment. Movement Disorders 25: 1568-1576.

  152. Lodge, D.J. and Grace, A.A. (2010) Developmental pathology, dopamine, stress and schizophrenia. International Journal of Developmental Neuroscience (in press).

  153. Lipski, W.J. and Grace, A.A. (2010) Ventral hippocampal-medial prefrontal cortical synaptic plasticity is selectively modified by contextual fear conditioning. (submitted).

  154. Cifelli, P. and Grace, A.A. (2010) Pilocarpine induced temporal lobe epilepsy in the rat is associated with increased dopamine neuron activity. (submitted).

  155. Moses-Kolko, E.L., Meltzer, C.C., Lanza di Scalea, T., Kaye, W., Price, J.C., Grace, A.A., Berga, S.L., Mathis, C.A., Drevets, W.C., Hanusa, B.H., Becker, C. and Wisner, K.L. (2010) Relationship of depression and [11C]raclopride binding to D2/3 receptors is moderated by postpartum status in unipolar depressed women. (submitted).

  156. Gill, K.M. and Grace, A.A. (2010) Heterogeneous processing of amygdala and hippocampal inputs in the rostral and caudal subregions of the nucleus accumbens (submitted).

  157. Valenti, O., Lodge, D.J. and Grace, A.A. (2010) Aversive stimuli alter ventral tegmental area dopamine neuron activity via a common action in the ventral hippocampus (submitted).

  158. Lodge, D.J. and Grace, A.A. (2010) Divergent activation of ventromedial and ventrolateral dopamine systems in animal models of amphetamine sensitization and schizophrenia. (submitted).





Book Chapters and Reviews

  1. Grace, A.A.(1977) Techniques in Neurobiological Research. Allegheny College Printing, Meadville, PA. pp.1-165.

  2. Bunney, B.S.and Grace, A.A.(1979) Effects of chronic haloperidol treatment on nigral dopaminergic cell activity. In: Catechola­mines: Basic and Clinical Frontiers. Eds.E.Usdin, I.J.Kopin and J.Barchas, Pergamon Press, New York, pp.666-668.

  3. Bunney, B.S., Grace, A.A.and Hommer, D.W.(1980) Changing concepts of nigral dopamine system function within the basal ganglia. J. Neural Trans. (Suppl.16):17-23.

  4. Bunney, B.S., Skirboll, L.R.and Grace, A.A.(1980) Acute and chronic haloperidol treatment: Effects on nigrostriatal dopamin­ergic system activity. Adv. Biochem. Psychopharmacol. 24:267-27­3.

  5. Skirboll, L.R., Hökfelt, T., Grace, A.A., Hommer, D.W., Rehfeld, J.F., Markey, K., Goldstein, M.and Bunney, B.S.(1981) The co-exis­tence of dopamine and a CCK-like peptide in a subpopulation of midbrain neurons: Immunocytochemical and electrophysiological studies. In: Apomorphine and other Dopaminomimetics. Vol. 1: Basic Pharmacology. Eds.G.L.Gessa and G.U.Corsini. Raven Press, New York, pp.65-77.

  6. Bunney, B.S., Grace, A.A., Hommer, D.W.and Skirboll, L.R.(1982) Effect of cholecystokinin on the activity of midbrain dopaminergic neurons. In: Advances in Biochemical Psychopharmacology, Vol. 32. Eds.E.Costa and M.Trabucci. Raven Press, New York, 429-437.

  7. Grace, A.A.and Bunney, B.S.(1984) Nigral dopaminergic neurons: Extracellular and intracellular electrophysiological character­istics. In: Catecholamines: Neuropharmacology and Central Nervous System - Theoretical Aspects. Eds.E.Usdin, A.Carlsson, A.Dahlström and J.Engel. Alan R.Liss, Inc.,New York, 323-332.

  8. Bannon, M.J., Chiodo, L.A., Bunney, E.B., Wolf, M.E., Grace, A.A., Bunney, B.S.and Roth, R.H.(1984) In vivo biochemical and electro­physio­logical studies on the distribution and pharmacology of dopamine autoreceptors. In:Catecholamines: Neuropharmacology and Central Nervous System - Theoretical Aspects. Eds.E.Usdin, A.Carlsson, A.Dahlström and J.Engel. Alan R.Liss, Inc., New York, 25-36.

  9. Grace, A.A.and Bunney, B.S. (1984) Striatal modulation of dopamine neuron firing. Clinical Neuropharmacol. 7 (Suppl.1):64-65.

  10. Bunney, B.S., Grace, A.A.and Meltzer, L.T.(1984) Midbrain dopamin­ergic neurons: A new model of their functioning? Clinical Neuropharm­acol. 7 (Suppl.1):92-93.

  11. Grace, A.A.and Bunney, B.S.(1985) Dopamine. In: Neurotransmitter Actions in the Vertebrate Nervous System. Eds.J.L.Barker and M.A.Ro­gawski, Plenum Publishing Corp., New York, 285-319.

  12. Bunney, B.S., Chiodo, L.A., Grace, A.A.and Schenk, J.O.(1985) In vivo effects of acute and chronic antipsychotic drug administra­tion on midbrain dopaminergic neuron activity. In: Behavioral Pharmacology: The Current Status. Eds.R.Balster and L.Seiden. Alan R.Liss, Inc., New York, 205-220.

  13. Grace, A.A. (1987) Commentary: An electrophysiologist's eye view of the basal ganglia. Behavioral Brain Sci. 10: 197-245.

  14. Grace, A.A. (1987) The regulation of dopamine neuron activity as determined by in vivo and in vitro intracellular recordings. In: The Neurophysiology of Dopamine Systems. Eds. Chiodo, L.A. and Freeman, A.S. Lake Shore Publications, Detroit, pp. 1-67.

  15. Grace, A.A. (1988) In vivo and in vitro intracellular recordings from dopamine neurons. Annals of the New York Academy of Sciences: The Mesocorticolimbic Dopamine System Vol. 537: 51-76.

  16. Berger, T.W., Nisenbaum, E.S., Onn, S.-P. and Grace, A.A. (1990) Pharmacological and morphological properties of two functionally distinct subpopulations of striatal neurons. In: The Basal Ganglia III. Ed. G. Bernardi, M.B. Carpenter, G. DiChiara, M. Morelli and P. Stanzione, Plenum Press, New York; Advances in Behavioral Biology 60: 335-345.

  17. Grace, A.A. (1991) The modulation of dopamine system responsivity by cortically regulated extracellular dopamine levels: A hypothesis for the etiology of schizophrenia. Posters in Neuroscience 1: 3-8.

  18. Smith, I.D. and Grace, A.A. (1991) Subthalamic nucleus afferents to the substantia nigra regulate dopamine neuron burst firing. Posters in Neuroscience 1: 25-28.

  19. Nisenbaum, E.S., Grace, A.A. and Berger, T.W. (1991) Differential contribution of D1 and D2 dopaminergic receptors to the response properties of two functionally distinct subpopulations of striatal neurons. Posters in Neuroscience 1: 59-66.

  20. Zigmond, M.J., Abercrombie, E.D., Berger, T.W., Grace, A.A. and Stricker, E.M. (1993) Compensatory responses to partial loss of dopaminergic neurons: Studies with 6-hydroxydopamine. In: Current Concepts in Parkinson's Disease Research. Ed. J.S. Schneider & M. Gupta, Hogrefe & Huber Publishers, Toronto, pp. 99-140.

  21. Onn, S.-P., Pucak, M.L. and Grace, A.A. (1993) Lucifer yellow dye labeling of living nerve cells and subsequent immunoperoxidase staining with Lucifer yellow antiserum. Neuroscience Protocols: 93-050-17.

  22. Pucak, M.L. and Grace, A.A. (1994) The regulation of substantia nigra dopamine neurons. Critical Reviews in Neurobiology 9: 67-89.

  23. Grace, A.A. and Bunney, B.S. (1995) Electrophysiology. In: American Psychiatric Press Textbook of Psychopharmacology. Ed. C.B. Nemeroff and A.F. Schatzberg, American Psychiatric Press, Washington, D.C. pp. 65-79.

  24. Grace, A.A. and Bunney, B.S. (1995) Electrophysiological properties of midbrain dopamine neurons. In: Psychopharmacology: The Fourth Generation of Progress. Ed. F.E. Bloom and D.J. Kupfer, Raven Press, New York, pp. 163-177.

  25. O’Donnell, P. and Grace, A.A. (1996) Basic neurophysiology of antipsychotic drug action. Chapter 16. In: Handbook of Experimental Pharmacology: Antipsychotics. Ed. J.G. Csernansky, Springer-Verlag, Heidelberg, pp. 163-202.

  26. Grace, A.A. (1996) Thalamocortical aspects of consciousness from the perspective of a neurobiologist: A commentary on J. Newman's "Thalamocortical Foundations of Conscious Experience" E-Seminar at URL: http://server.phil.vt.edu/ASSC/newman/grace.html

  27. Grace, A.A. (1996) Chapter 13: Gating of information flow through limbic and thalamocortical systems: Implications for the pathophysiology of schizophrenia. In: Schizophrenia: Latest Advances in Understanding and Drug Development. Ed. L. Dirks, IBC Biomedical Library, Southborough, MA pp. 1.3.1-1.3.25.

  28. Grace, A.A., Moore, H. and O’Donnell, P. (1997) The modulation of corticoaccumbens transmission by limbic afferents and dopamine: A model for the pathophysiology of schizophrenia. In: Catecholamines: Bridging Basic Science with Clinical Medicine; Advances in Pharmacology 42: 721-724.

  29. Grace, A.A., Gerfen C.R. and Aston-Jones, G. (1997) Theme F: Catecholamines in the central nervous system: Overview. In: Catecholamines: Bridging Basic Science with Clinical Medicine; Advances in Pharmacology 42: 655-670.

  30. Grace, A.A., Todd, C.L. and Moore, H. (1997) Glutamatergic effects and depolarization block - Reply. Trends in Neurosciences 20: 394-395.

  31. Grace, A.A. (1997) Temporal correlates of binding and associations: Are they system-specific? A commentary on Engel, A.K., Fries, P., Roelfsema, R., Konig, P. and Singer, W. ATemporal binding, binocular rivalry, and consciousness. E-Seminar at URL: http://server.phil.vt.edu/ASSC/engel/grace1.html

  32. Grace, A.A. and Bunney, B.S. (1998) Electrophysiology. In: American Psychiatric Press Textbook of Psychopharmacology, Second Edition. Ed. C.B. Nemeroff and A.F. Schatzberg, American Psychiatric Press, Washington, D.C. pp. 75-88.

  33. Czernansky, J.G. and Grace, A.A. (1998) Editors, New Pathophysiological Models of Schizophrenia. Special Issue of Schizophrenia Bulletin Volume 24 (2) pp. 185-316.

  34. Czernansky, J.G. and Grace, A.A. (1998) New models of the pathophysiology of schizophrenia: Editors’ introduction. Schizophrenia Bulletin 24: 185-187.

  35. Grace, A.A. (1998) Multiple Mechanisms for the Regulation and Gating of Affect within the Basal Ganglia and Thalamocortical System. E-Seminar at URL: http://www.phil.vt.edu/ASSC/watt/grace1.html

  36. O’Donnell, P. and Grace, A.A. (1999) Disruption of information flow within cortical-limbic circuits and the pathophysiology of schizophrenia. Review of Psychiatry, Vol. 18: Schizophrenia in a Molecular Age, Ed. C.A. Tamminga, American Psychiatric Press, Inc., Washington, DC, pp. 109-140.

  37. Todd, C.L. and Grace, A.A. (1999) Modulation of ventral tegmental area dopamine cell activity by the ventral subiculum and entorhinal cortex. Annals of the New York Academy of Sciences: Advancing from the Ventral Striatum to the Extended Amygdala. Vol. 877: 688-690.

  38. O’Donnell, P., Green, J., Pabello, N., Lewis, B.L. and Grace, A.A. (1999) Modulation of cell firing in the nucleus accumbens. Annals of the New York Academy of Sciences: Advancing from the Ventral Striatum to the Extended Amygdala. Vol. 877: 157-175.

  39. Moore, H., West, A.R. and Grace, A.A. (1999) The regulation of forebrain dopamine neurotransmission: Relevance to the pathophysiology of schizophrenia. Biological Psychiatry 46: 40-55.

  40. Grace, A.A. (2000) Gating of information flow within the limbic system and the pathophysiology of schizophrenia. Proceedings from the Nobel Symposium - Schizophrenia: Pathophysiological Mechanisms. Brain Research Reviews 31: 330-341.

  41. West, A.R. and Grace, A.A. (2001) The role of frontal-subcortical circuits in the pathophysiology of schizophrenia. In: Frontal-Subcortical Circuits in Neurology and Psychiatry, Ed. D.G. Lichter, Guilford Press, New York 372-400.

  42. Grace, A.A. (2001) Psychostimulant actions on dopamine and limbic system function: Relevance to the pathophysiology and treatment of ADHD. In: Stimulant Drugs and ADHD: Basic and Clinical Neuroscience. M. V. Solanto, A.F.T. Arnsten and F.X. Castellanos (Eds.) Oxford University Press, New York 134-157.

  43. Grace, A.A. (2002) Dopamine. In: Neuropsychopharmacology: The Fifth Generation of Progress. Ed. D. Charney, J. Coyle, K. Davis and C. Nemeroff. Lippincott, Williams and Wilkins, Raven Press, New York pp. 119-132.

  44. Rosenkranz, J.A. and Grace, A.A. (2002) Regulation of conditioned responses of basolateral amygdala neurons. Physiology and Behavior 77: 489-493.

  45. Rosenkranz, J.A. and Grace, A.A. (2003) Affective conditioning in the basolateral amygdala of anesthetized rats is modulated by dopamine and prefrontal cortical inputs. In: The Amygdala in Brain Function. Annals of the New York Academy of Sciences 985: 488-491.

  46. Grace, A.A., Rosenkranz, J.A. and West, A.R. (2003) Electrophysiology. In: American Psychiatric Press Textbook of Psychopharmacology, Third Edition. Ed. C.B. Nemeroff and A.F. Schatzberg, American Psychiatric Press, Washington, D.C. pp. 89-103.

  47. West, A.R., Floresco, S.B., Charara, A., Rosenkranz J.A. and Grace, A.A. (2003) Electrophysiological interactions between striatal glutamatergic and dopaminergic systems. In Glutamate and Disorders of Cognition and Motivation. Vol. 1003, Annals of the New York Academy of Sciences; ed. B. Moghaddam & M.E. Wolf. pp 53-74.

  48. Grace, A.A. (2003) Forebrain dopamine systems: can they help us to understand psychosis? European Psychiatry 18: 27s-31s.

  49. Grace, A.A. (2004) Schizophrenia represents a failure to regulate dopamine systems. In: Schizophrenia - Challenging the Orthodox. Ed: C. McDonald, K. Schulze, R. M. Murray, & P. Wright. Martin Dunitz Publishers, London, UK pp. 137-144.

  50. Grace, A.A. (2004) Developmental dysregulation of the dopamine system and the pathophysiology of schizophrenia. In Neurodevelopment and Schizophrenia. M. Keshavan, JL Kennedy & R.M. Murray, eds. Cambridge University Press pg. 273-294.

  51. Grace, A.A. (2006) Disruption of cortico-limbic interaction as a substrate for comormidity. Neurotoxicity Research 10: 93-101.

  52. Agid, Y., Buzsaki, G., Diamond, D.M., Frackowiak, R., Giedd, J., Girault, J.A., Grace, A.A., Lambert, J.J., Manji, H., Mayberg, H., Popoli, M., Prochiantz, A., Richter-Levin, G., Somogyi, P., Spedding, M., Svenningsson, P. and Weinberger, D. (2007) How can drug discovery for psychiatric disorders be improved? Nature Reviews/Drug Discovery 6: 189-201.

  53. Laviolette, S.R. and Grace, A.A. (2006) The roles of cannabinoid and dopamine receptor systems in neural emotional learning circuits: Implications for schizophrenia and addiction. Cellular and Molecular Life Sciences 63: 1597-1613.

  54. Grace, A.A. (2007) Stress-induced pathophysiology within the schizophrenia patient brain: A model for the delayed onset of psychosis and its circumvention by anxiolytic agents. Adolescent Brain and Psychopathology: Integrating Brain and Prevention Science. Ed. D. Romer & E.F. Walker. Oxford University Press, pp. 245-263.

  55. Goto, Y. and Grace, A.A. (2007) The dopamine system and the pathophysiology of schizophrenia: A basic science perspective. In: Integrating the Neurobiology of Schizophrenia. Ed: A. Abi-Dargham & O. Guillin. International Review of Neurobiology 78: 42-58.

  56. Belujon, P., Lodge, D.J. and Grace, A.A. (2007) Dopamine systems in Parkinson’s disease and L-DOPA induced dyskinesias – what goes wrong? US Neurological Disease 2007, Volume II 56-58.

  57. Lodge, D.J. and Grace, A.A. (2008) Hippocampal dysfunction and disruption of dopamine system regulation in an animal model of schizophrenia. Neurotoxicity Research 14: 97-104.

  58. Lodge, D.J., Buffalari, D.M. and Grace, A.A. (2009) Dopamine: CNS pathways and neurophysiology. In: Encyclopedia of Neuroscience. Ed: L.R. Squire, pp. 549-555.

  59. Heinz, A., Beck, A., Grusser, S.M., Grace, A.A. and Wrase, J. (2009) Identifying the neuronal circuitry of alcohol craving and relapse vulnerability. Addiction Biology 14: 108-118.

  60. Heinz, A., Grace, A.A. and Beck, A. (2009) The intricacies of dopamine neuron modulation. Biological Psychiatry 65: 101-102.

  61. Grace, A.A., Rosenkranz, J.A. and West, A.R. (2009) Electrophysiology. In: American Psychiatric Press Textbook of Psychopharmacology, Fourth Edition. Ed. C.B. Nemeroff and A.F. Schatzberg, American Psychiatric Press, Washington, D.C. pp. 135-151.

  62. Lodge, D.J. and Grace, A.A. (2009) Gestational methylazoxymethanol acetate administration: a developmental disruption model of schizophrenia. Behavioral Brain Research 204:306-12.

  63. Grace, A.A. (2009) Animal models of schizophrenia: Focus on hippocampal disruption of dopamine system regulation. In: Advances in Schizophrenia Research 2009. Eds. W.F. Gattaz, & G. Busatto, Springer-Verlag pp. 175-191.

  64. Grace, A.A. (2009) DA modulation of forebrain pathways and the pathophysiology of psychiatric disorders. Dopamine Handbook. Ed. A. Bjorklund, L. Iversen, and S. Iversen. Oxford University Press, pp. 590-598.

  65. Heinz, A., Beck, A., Mir, J., Grusser, S.M., Grace, A.A. and Wrase, J. (2010) Alcohol craving and relapse prediction – imaging studies. In: Advances in the Neuroscience of Addiction. Ed. C.M. Kuhn & G. Koob. CRC Press, pp. 137-161.

  66. Grace, A.A. (2010) Hippocampal dysregulation of dopamine system activity as a pathophysiological basis for psychosis in schizophrenia. Clinical Psychopharmacology and Neuroscience 8: 1-9.

  67. Grace, A.A. and Sesack, S. (2010) The cortico-basal ganglia reward network: Microcircuitry. Neuropsychopharmacology 35: 4-26.

  68. Grace, AA. (2010) Anatomy and physiology of limbic system dysfunction in Parkinson’s Disease. Ed. W. Olanow. (in press).

  69. Grace, A.A. and Abi-Dargham, A. (2010) Dopamine and Schizophrenia. In: Schizophrenia. Ed. D. Weinberger & S. Hirsch, Blackwell Press (in press).

  70. Grace, AA (2010) Dopamine system dysregulation by the ventral subiculum as the common pathophysiological basis for schizophrenia psychosis, psychostimulant abuse, and stress. Neurotoxicity Research (in press).

  71. Beck, A., Grace, A.A., and Heinz, A. (2010) Reward Processing. In: Neuroimaging in the Addictions. Ed. B. Adinoff and E.A. Stein (in press).

  72. Grace, A.A. (2010) Dopamine modulation of decision-making processes. In: New Horizons in the Neuroscience of Consciousness. Ed. E. Perry, D. Collerton, F. LeBeau and H. Ashton. John Benjamins Publishing Company, Amsterdam, Netherlands (in press).

  73. Belujon, P. and Grace, A.A. (2010) Hippocampus, amygdala and stress: Interacting systems that affect susceptibility to addiction. (submitted).