Name: Steve Arnoczky, D.V.M.
Affiliation: Michigan State University
Title: Wade O. Brinker Professor of Veterinary Surgery
Director, Laboratory for Comparative Orthopaedic Research
Professor of Orthopaedic Surgery, College of Human Medicine
Professor of Surgery, College of Osteopathic Medicine


Professional Summary:
After spending 16 years in New York City where he was a Professor of Comparative Orthopaedic Surgery at the Cornell University Medical School and a Senior Scientist at the Hospital for Special Surgery, Dr. Arnoczky was appointed as the first Wade O. Brinker Professor of Veterinary Surgery at Michigan State University in 1992. In this position he directs the Laboratory for Comparative Orthopaedic Research which is dedicated to the basic science investigation of musculoskeketal tissues in all species. Dr. Arnoczky's research centers around the injury and repair of ligaments, tendons, and cartilage in humans and animals. Dr. Arnoczky's research in comparative orthopaedics has resulted in numerous awards and honors from both the human and veterinary medical community. He has been recognized for outstanding research by the American Academy of Orthopaedic Surgeons and The American Orthopaedic Society for Sports Medicine. In addition, he has been the recipient of the Purina Small Animal Research Award and the SmithKline Beecham Award for Research Excellence. Dr. Arnoczky has also received the outstanding alumnus award from The Ohio State University College of Veterinary Medicine, the Distinguished Alumni Award from the Animal Medical Center, and the National Gamma Award from the Omega Tau Sigma fraternity for distinguished contributions to the veterinary profession. In 1999 Dr. Arnoczky was a recipient of the Distinguished Faculty Award from Michigan State University.

Dr. Arnoczky has published over 300 scientific papers and has received over 2 million dollars in research support. He holds adjunct appointments in both the College of Human Medicine and the College of Osteopathic Medicine and is a frequent speaker at orthopaedic surgery meetings both here and abroad. He has published over 300 scientific articles and has edited books on the basic science of ligaments and cartilage.

Dr. Arnoczky's current research includes the investigation of overuse injuries in tendons, development of a tissue engineered tendons and menisci, and the evaluation of various synthetic bone grafts.

Educational Background:
DVM, College of Veterinary Medicine, The Ohio State University, Columbus, OH, 1972

Lab Contact Info:
Steven P. Arnoczky, DVM
College of Veterinary Medicine, G-387
Michigan State University
East Lansing, MI 48824
Phone: (517) 353-8964
Fax: (517) 353-8980
Email: arnoczky@cvm.msu.edu
www.cvm.msu.edu/LCOR

Research Interests:
  • The investigation of overuse injuries in tendons
  • Development of a tissue engineered tendons and menisci
  • The evaluation of various synthetic bone grafts
Publications:
Crawford MJ, Swenson CL, Arnoczky SP, O'Shea J, Ross H.: Lyophilization does not inactivate infectious retrovirus in systemically infected bone and tendon allografts. Am J Sports Med. 2004 Apr-May;32(3):580-6.

Arnoczky SP, Lavagnino M, Gardner K, Tian T, Vaupel ZM, Stick JA: In vitro effects of oxytetracycline on matrix metalloproteinase-1 mRNA expression and on collagen gel contraction by cultured myofibroblasts obtained from the accessory ligament of foals Am J Vet Res 65:491-496, 2004.

Crawford MJ, Swenson CL, Arnoczky SP, O'Shea JH, Ross H: Lyophilization does not inactivate infectious retrovirus in systemically infected musculoskeletal tissues. Trans Orthop Res Soc 29:1074, 2004.

Tian T, Lavagnino M, Gardner K, Arnoczky SP: Hyperthermia increases the magnitude of caspase-3 activation and DNA fragmentation in tendon cells undergoing cyclic strain: a potential intrinsic factor in the etiology of tendon overuse injury. Trans Orthop Res Soc 29: 881, 2004.

Lavagnino M, Arnoczky SP, Tian T, Gardner K: Gene expression and cytoskeletal tensional homeostasis: evidence for a mechanostat set point in tendon cells. Trans Orthop Res Soc 29:270, 2004.