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$\hbox{GABA}_A$

GABA-A is responsible for fast inhibition and require only brief stimuli to produce a response. The same simplified type of kinetic model used for AMPA synapses can be used for GABA-A. The current is

\begin{displaymath}
I_{GABA_A} = \bar{g}_{GABA_A} s(t)(V-V_{GABA_A}) \end{displaymath}

\begin{displaymath}
\frac{ds}{dt} = \alpha [T] (1-s) - \beta s\end{displaymath}

with $\alpha=5\ mM^{-1} ms^{-1}$, $\beta=.18 \ ms^{-1}$ and $V_{GABA_A}=-80 \ mV.$

G. Bard Ermentrout
2/12/1998