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Patricia Opresko - Grants
Years Title Position October 18-22, 2008 Awarded to support the symposia on “DNA Damage in Neurodegeneration, Aging and Cancer” and “Consequences of Genotoxic Damage to Mitochondrial DNA” and the plenary lecture by Dr. Jerry Shay on “Aging and Cancer: Are Telomeres and Telomerase the Connection?” at the 39th Annual Meeting of the Environmental Mutagen Society held October 18-22, 2008 in Rio Grande, Puerto Rico
Principal Investigator August 20 - 25, 2009 Awarded to support the symposia on “DNA Damage Repair and Aging” at the 10th International Conference on Environmental Mutagens held in Florence, Italy Principal Investigator 2009 - 2011 Mechanisms of Telomeric DNA Loss and Repair, Supplement Principal Investigator 2010 - 2013 Processing of Alternative Structures in Telomeric DNA". Award to student Gerald Nora Principal Investigator 2006-2010 Molecular Mechanisms of Telomeric DNA Instability Associated with the Human Progeroid Werner Syndrome Principal Investigator 2008-2010 Relationship of Age-Related Cataracts and Telomere Length in HumanCollaboration with Dr. Ann Newman at the University of Pittsburgh Principal Investigator 2006-2013 Mechanisms of Telomeric DNA Loss and Repair Principal Investigator 2011 - 2014 The Center for Nucleic Acids Science and Technology: An Interdisciplinary Research Center Co-Principal Investigator 2010 - 2012 Impact of UV-induced DNA damage on telomere integrity
Principal Investigator 2010 - 2013 Kirschstein-NRSA Individual Fellowship, 1F30AG032861-01A1 "Processing of Alternative Structures in Telomeric DNA" Award to student Gerald Nora
Co-Principal Investigator 2013 - 2018 R01ES022944/ Mechanisms of Telomere Resistance to DNA Lesion Removal Principal Investigator 7/2013-7/2014 Role of Telomere and Mitochondria Cross-talk in Cellular Aging Co-Principal Investigator 7/1/2013-6/30/2015 R34GM108187/GammaPNA Miniprobes for Telomere FISH Co-Principal Investigator 7/1/2013-6/30/2015
R21AG045545/Oxidative DNA Base Damage and Repair at Telomeres and the Relevance to Cell Senescence Co-Principal Investigator 2015 - 2020 R21ES025606/ROS Driven Mitochondrial-Telomere Dysfunction During Environmental Stress Co-Principal Investigator 2015 - 2018 R34 Phase II – GammaPNA Miniprobes for Telomere Analysis and RNA FISH Co-Principal Investigator 2016 - 2017 Investigating a non-canonical function of DNA polymerase eta in the maintenance of telomere integrity Co-Principal Investigator 2017 - 2022 R01CA207342/ Roles of Telomere Oxidative DNA Lesions in Telomere Length Co-Principal Investigator 2016 - 2018 Creating transgenic mice to illuminate roles for mitochondrial and telomere damage in cancer and aging Co-Principal Investigator 2016 - 2019 R44GM108187 Phase II – GammaPNA Miniprobes for Telomere Analysis and RNA FISH Co-Principal Investigator