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dept. of structural biology



Solid State NMR

Protein & Amyloid

Protein-Lipid Interaction

SSNMR Methods




Selected Links

Contact info

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1. Graduate students in the MBSB program & postdoctoral research

There are ongoing opportunities for graduate students and/or postdocs to join us. People interested in pursuing biological solid state NMR research within the Molecular Biophysics & Structural Biology graduate program and postdoctoral candidates interested in such work are encouraged to contact me at pvdwel@pitt.edu. I will be glad to provide any further information as requested.

2. Additional information

Our research group uses solid state NMR to study various biological topics, predominantly through the use of magic angle spinning (MAS) solid state NMR. Particular interests are focused on the structural and biophysical characterization of proteins: (1) Membrane protein studies focused on the interplay between the lipids of the lipid bilayer and the membrane-bound protein, and the importance of this interaction for the structure and function of the biological membrane. (2) Investigations into the common features of amyloid fibril structure and formation. See also the links to the left, for further background information.

Location / Department
The Department of Structural Biology features collaborative research groups that address structural biology through a variety of techniques, with expertise in amyloid studies, solution state NMR, (cryo) EM, and X-ray crystallography. It is housed in a new research building and includes state-of-the-art equipment and wet lab resources. The solid state NMR group has specific access to Bruker 800 and 600 MHz magnets, which are well-equipped with multiple MAS as well as static solid state NMR probes. See here for more information on the extensive liquid- and solid-state NMR resources of the department. Located within or near the campuses of the University of Pittsburgh, the UPMC medical center, and Carnegie Mellon University, it finds itself in a scientifically stimulating environment. The city of Pittsburgh provides a top-rated yet affordable place to live.