| collection | slide # | label |
description |
| Stomach |
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| sections from cardiac (ring
around entrance of esophagus) or fundus (bulge above), body (below fundus),
and pyloric regions (gatekeeper: entry to intestine): rugae (temporary folds)
but no villi! surface mucous epithelium dips into gastric pits (foveolae)
at isthmus of glands; mucosa: mucous cells (mucocytes), lamina propria,
muscularis mucosae (inner circular, outer longitudinal = strands between
glands and pits); neck of gland: neck mucous cells, mitotic figures = stem
(regenerative) cells; base of gland: enteroendocrinocytes (known as amine
precursor uptake and decarboxylation [APUD] cells or diffuse neuroendocrine
system [DNES] cells); submucosa, mucous or gut associated lymphoid tissue
(MALT or GALT); submucosal (Meissner's) plexus; muscularis externa (oblique,
circular, longitudinal; myenteric (Auerbach's) plexus; serosa |
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| Dig. Sys | 4508 | Stomach composite: sec | cardiac/fundic: length gastric pits equal
to or less than that of glands; pits broad; cardiac glands simple and branched
tubular, may be coiled basally, dominated by mucous cells with occasional
parietal (oxyntic) cells in upper half of gland; esophageal glands may run
over into cardiac portion of stomach; body (also called fundic): branches open into shallow, narrow gastric pits (shorter than glands); gastric (also called fundic) glands: mucous neck cells (between parietal cells), parietal (fried egg [negative image of canaliculli], secrete hydrochloric acid, gastric intrinsic factor [in human beings]) in outer portion, and chief (zymogenic: secrete pepsinogen, renin, lipase) cells in lower portion, enteroendocrinocytes (APUD: secrete serotonin) in base; MALT pyloric: length gastric pits greater than that of glands; pits broad branched, coiled tubular pyloric glands of mucous cells (secrete mucus and lysozyme), parietal cells rare, no chief cells; enteroendocrinocytes (gastric secreting G cells and somatostatin secreting D cells); MALT; pyloric sphincter |
| Small
Intestine |
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| plicae circulares (permanent
folds involving mucosa and submucosa); villi (projections of mucosa): absorptive
epithelium with striated (brush) border, glycocalyx and terminal bars slough
off tip of villi, goblet cells, lamina propria with lacteals (lymphatic
capillaries), capillaries, gut-associated lymphoid tissue (GALT: macrophages,
lymphocytes, plasma cells, mast cells), muscularis mucosa: longitudinal
outer, circular inner, strands run into villi; submucosa, submucosal (Meissner's)
plexus (parasympathetic ganglia); muscularis externa (inner circular, outer
longitudinal), myenteric (Auerbach's) plexus; serosa (adventitia); intestinal
glands (crypts of Lieberkühn) open into intervillar space: intestinal
epitheliocytes, endocrinocytes (APUD cells), basal exocrinocytes (Paneth
cells [difficult to identify] secrete lysozyme), mitotic figures = stem
cells; serosa (mesothelium) or adventitia (fused to body wall) |
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| Dig. Sys | 4526 | Duodenum: c.s. | large, leaf-like (foliate) villi; moderate number
goblet cells; (submucosal) duodenal glands (Brunner's glands); |
| Dig. Sys |
4593 |
Bile duct mammal: c.s. | (same as 4526 except entry bile
duct through adventitia of duodenum); hepatopancreatic ampulla (ampulla
of Vater) and sphincter of hepatopancreatic ampulla (of Oddi) |
| Dig. Sys | 4530 | Jejunum: c.s. | plicae circulares (folds) most developed; large,
finger-like villi; increased number goblet cells |
| Dig. Sys | 4534 | Ileum: c.s. | short, finger-like villi; greatest number goblet
cells; aggregated lymphatic follicles or nodules (Peyer's patches),
M (microfold) cells |
| Large
Intestine |
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| Dig. Sys | 4542 or 4546 | Colon; H&E: c.s. | no pits or villi; abundant goblet
cells; absorptive cells; glands: enteroendocrinocytes; gut-associated lymphoid
tissue (GALT: macrophages, lymphocytes, plasma cells, mast cells), muscularis
mucosa (circular inner, longitudinal outer); submucosa, submucosal (Meissner's)
plexus (parasympathetic ganglia); muscularis externa (inner circular, outer
longitudinal); taniae coli (thickened bands of longitudinal muscle) separate
haustra coli (sacculations), myenteric (Auerbach's) plexus and parasympathetic
ganglia; serosa or adventitia |
| Dig. Sys | 4558 | Recto-anal junction: l.s. | abrupt change in type epithelium:
simple columnar with goblet cells; stratified squamous of keratinizing type;
large perianal glands; adventitia; external sphincter (skeletal); internal
sphincter (smooth) |
| Dig. Sys | 6787 | Appendix human: c.s. | lymphatic follicles or nodules
in submucosa (germinal centers indistinct) |
| Liver, Gall Bladder
and Pancreas |
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| Dig. Sys | 4566 | Liver Pig: sec | septa (stroma) delineate classic lobules; portal
area (spaces); triad: hepatic artery (arteriole), portal vein, bile duct
(generally lymph vessel as well); terminal plate = peribiliary area = limiting
hepatocytes; parenchyma: hepatocytes (look for differences between perilobular
and centrolobular cells, e.g., binuclear centrolobular hepatocytes) surrounded
by bile canaliculi in plates (trabeculae), radiate from central vein (drain
into sublobular vein and ultimately hepatic vein); sinusoids (incomplete,
fenestrated endothelium) or discontinuous capillaries; bile ductules, cholangioles;
serosa (Glisson's capsule) |
| Dig. Sys | 4582 | Phagocytosis: sec | hepatic fixed macrophages (Kupffer's
cells) with ingested ink particles in subendothelial space (space of Disse) |
| Dig. Sys | 4590 | Gall bladder: c.s. | tall, columnar epithelium; primary bile duct; lamina
propria; muscularis externa; serosa; common bile duct |
| Dig. Sys | 4600 | Pancreas: sec | exocrine: serous acini: apical secretory
(zymogen) granules and basal basophilia; vesicular nuclei; no pericytes (myoepithelial
cells); centroacinar cells and intercalated ducts (difficult to distinguish
except by absence of secretory granules); interlobular ducts with increasing
amounts of connective tissue and stratified cuboidal epithelium. endocrine (pancreatic islets = islets of Langerhans): polarized endocrinocytes; capillaries note lamellated (Pacinian) corpuscle in some sections |