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This circumstance turns the procedure of validating quality of life scales into a potentially infinite process which is presented in the last line of Table 4. The essence of the process consists in a comparative study of two and more instruments on a unified sample of patients with a subsequent modification of the instruments. Such a prolonged and laborious procedure requires an even greater integration of the researchers� efforts on the international scale. At the same time it becomes more and more obvious that such integration presupposes the development of a unified notion system that would be unambiguously interpreted and understood by all researchers.