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•National
average IFR variation well over an order of magnitude
•Range from 0.06% (Uganda) to 1.2% (Japan)
•
•Clear
regional separation of mortality and predicted spread of
infections
•South America showing infections spread 20-40%
•Europe and North America with infections
spread 2-20%
•Significant internal European variability
•Sub-Saharan Africa very low levels of
infection spread (<2%) with exception South Africa which has
much higher age distribution
•Limited infection spread in East Asia and SE
Asia (<5%)
•
•Hypothesised
proportion of population infected mostly higher than
reported sero-prevalence data
•
•Explanations,
other than spread of infection, for regional variations in
mortality levels might be a combination of: data
imperfections, seasonal variations, variability in public
health controls, differences in level of prior immunity from
exposure to other seasonal coronaviruses, socio-economic
differences, and prevalence of other co-morbidities
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