Episodic Ataxia (EA) pedigree: NPL
Results of the Non-Parametric Linkage (NPL) Analysis from SimWalk2 2.91
The results for the pedigree named: 20 ##
which is pedigree number: 001 ##
This run has the integer label: 33 ##
The number of individuals is: 29
The number of affecteds is: 12
Please see the overall NPL analysis output file: STATS-33.ALL
for a brief description of the statistics in the following tables.
BLOCKS MAX-TREE ENTROPY NPL_PAIR NPL_ALL
RECESSIVE DOMINANT STATISTIC ADDITIVE ADDITIVE
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RUN PED PEDIGREE MARKER P-VALUE P-VALUE P-VALUE P-VALUE P-VALUE
NUM NUM NAME NAME -Log(P) -Log(P) -Log(P) -Log(P) -Log(P)
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33 001 20 S91 0.7917 0.0008 0.0188 0.0008 0.0008
0.1014 3.1211 1.7266 3.1086 3.1240
33 001 20 S100 0.8040 0.0007 0.0186 0.0007 0.0007
0.0947 3.1400 1.7304 3.1424 3.1485
33 001 20 CACNL1A1 0.8079 0.0018 0.0226 0.0019 0.0016
0.0927 2.7512 1.6451 2.7257 2.8005
33 001 20 S372 0.5764 0.0047 0.0235 0.0042 0.0025
0.2393 2.3244 1.6288 2.3817 2.6072
33 001 20 pY2/1 0.3926 0.0086 0.0265 0.0076 0.0042
0.4060 2.0655 1.5773 2.1169 2.3752
33 001 20 pY21/1 0.3831 0.0080 0.0253 0.0073 0.0042
0.4167 2.0969 1.5969 2.1367 2.3768
33 001 20 KCNA5 0.3807 0.0081 0.0247 0.0079 0.0044
0.4194 2.0915 1.6073 2.1024 2.3565
33 001 20 S99 0.3805 0.0078 0.0235 0.0079 0.0040
0.4196 2.1079 1.6289 2.1024 2.3979
33 001 20 S93 0.3871 0.0178 0.0375 0.0185 0.0115
0.4122 1.7495 1.4258 1.7320 1.9400
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MARKER , POSITION , -LOG10(p-values)
NAME , in Haldane cM , BLOCKS , MAX-TREE, ENTROPY , NPL_PAIR, NPL_ALL
S91 , 0.0000 , 0.101 , 3.121 , 1.727 , 3.109 , 3.124 ##
S100 , 1.0101 , 0.095 , 3.140 , 1.730 , 3.142 , 3.148 ##
CACNL1A1 , 2.0203 , 0.093 , 2.751 , 1.645 , 2.726 , 2.801 ##
S372 , 5.1140 , 0.239 , 2.324 , 1.629 , 2.382 , 2.607 ##
pY2/1 , 8.2078 , 0.406 , 2.066 , 1.577 , 2.117 , 2.375 ##
pY21/1 , 9.2179 , 0.417 , 2.097 , 1.597 , 2.137 , 2.377 ##
KCNA5 , 10.2281 , 0.419 , 2.092 , 1.607 , 2.102 , 2.357 ##
S99 , 11.2382 , 0.420 , 2.108 , 1.629 , 2.102 , 2.398 ##
S93 , 12.2484 , 0.412 , 1.749 , 1.426 , 1.732 , 1.940
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