Training and Career Development:
Dr. Steinman is highly involved in the teaching of fellows, residents, MD-PhD, medical and graduate students. We very much wish to make the laboratory experience fun and informative and to provide an environment in which students can flourish. The philosophy of the laboratory is that close mentoring and clearly defined goals are optimal both for the career of the student and the trajectory of the laboratory.
Graduate rotations have the following components:
A discrete, hypothesis-driven project with a reasonable timetable for execution. Participation in weekly laboratory meetings and a weekly journal club. Presentation of work at the end of the rotation. Completion of an informal literature review relevant to the project. Graduate students undertaking thesis work in the Steinman laboratory and Hem-Onc fellows are expected in addition to co-author a review article, plan and write a mentored research grant, and learn how to critique manuscripts and proposals. They will present their own research project in laboratory meetings, scientific meetings and of course (for graduate students) to their thesis committee.
Examples of rotation projects include the following:
TAT peptide modulation of cyclin complex formation. Requirement for a sbp protein for neutrophil differentiation. Neutrophil segmentation in the absence of a chromatin crosslinker. Stat binding targets in response to distinct stimuli. Effect of p27 expression constrained to distinct subcellular domains. Sequence constraints of short interfering RNA.