PUBLICATIONS
(click
here for an up-to-date Pubmed search)
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| 2015 |
Wier GM, McGreevy EM,
Brown MJ, Boyle JP. New Method for the Orthogonal Labeling
and Purification of Toxoplasma
gondii Proteins While Inside the Host Cell.
(2015) MBio 6(2). pii: e01628-14. doi:
10.1128/mBio.01628-14. Link
to open access article. |
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Review: English
ED, Adomako-Ankomah Y, Boyle JP. Secreted effectors in Toxoplasma gondii
and related species: determinants of host range and pathogenesis?
(2015) Parasite Immunol. 37(3):127-40. doi:
10.1111/pim.12166. Link
to open access article. |
| 2014 |
Walzer KA, Wier GM, Dam
RA, Srinivasan AR, Borges AL, English ED, Herrmann DC, Schares G, Dubey
JP and Boyle JP. Hammondia hammondi harbors
functional orthologs of the host-modulating effectors GRA15 and ROP16
but is distinguished from Toxoplasma gondii by a
unique transcriptional profile.
Eukaryot Cell. 13(12):1507-18. doi:
10.1128/EC.00215-14. Epub 2014 Oct 3. |
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Bayer A, Delorme-Axford E, Sleigher C, Frey TK,
Trobaugh DW, Klimstra WB, Emert-Sedlak LA, Smithgall TE, Kinchington
PR, Vadia S, Seveau S, Boyle JP, Coyne CB, Sadovsky Y.
(2014) Human trophoblasts confer resistance to viruses
implicated
in perinatal infection. American Journal of Obstetrics and
Gynecology. Aug 6. pii: S0002-9378(14)00809-6. |
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Morgado P, Sudarshana D,
Gov L, Harker
K, Lam T, Casali P, Boyle JP, and Lodoen M. (2014).
Type II Toxoplasma
gondii
induction of CD40 on infected macrophages enhances IL-12
responses. Infection and Immunity. Jul 14. pii: IAI.01615-14.
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Pernas
L, Adomako-Ankomah Y, Shastri AJ, Ewald SE, Treeck M, Boyle JP,
Boothroyd JC. (2014) Toxoplasma
effector MAF1 mediates recruitment of host mitochondria and impacts the
host response. PLoS Biology. 12(4):e1001845. Link
to open access article.
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Adomako-Ankomah
Y, Wier GM, Borges AL, Wand HE and Boyle JP.
(2014) Differential locus expansion distinguishes Toxoplasmatinae
species and closely related strains of Toxoplasma
gondii.
MBio 5(1):e01003-13. Link
to open access article.
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Latorraca NR, Callenberg KM, Boyle JP and Grabe
M. Continuum approaches to understanding ion and Peptide
interactions with the membrane. (2014) Journal of
Membrane
Biology. May;247(5):395-408. Link to article. |
| 2013 |
Walzer
KA, Adomako-Ankomah Y, Dam RA, Herrmann DC, Schares G, Dubey JP, and
Boyle JP.
(2013) Hammondia hammondi,
an avirulent relative of Toxoplasma
gondii, has functional
orthologs of known T. gondii
virulence genes. Proc Natl Acad Sci U S A 110:7446-7451.
Link to article.
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Feliu
V, Vasseur V, Grover HS, Chu HH, Brown MJ, Wang J, Boyle JP,
Robey EA, Shastri N, Blanchard N. (2013) Location of the CD8 T cell
epitope within the antigenic precursor determines immunogenicity and
protection against the Toxoplasma
gondii parasite. PLoS
Pathogens. 9(6):e1003449.
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Dubey
JP, Tilahun G, Boyle JP,
Schares G, Verma SK, Ferreira LR, Oliveira S, Tiao N, Darrington C, and
Gebreyes WA. (2013) Molecular and Biological Characterization of First
Isolates of Hammondia hammondi
from Cats from Ethiopia. Journal of Parasitology. 99:614-618.
Link to article.
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| 2012 |
Kamau
ET, Srinivasan AR, Brown MJ, Fair MG, Caraher EJ, and Boyle JP.
(2012) A focused small-molecule screen identifies 14 compounds with
distinct effects on Toxoplasma
gondii. Antimicrobial Agents
& Chemotherapy 56:5581-5590.
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Opinion
piece:
Reese ML and Boyle
JP. (2012) Virulence
without catalysis: How can a pseudokinase affect host cell
signaling? Trends in Parasitology. Feb;28(2):53-7. |
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Wasmuth
JD, Pszenny V, Haile S, Jansen EM, Gast AT, Sher A, Boyle
JP, Boulanger MJ, Parkinson
J, and Grigg ME. (2012) Integrated bioinformatic and targeted deletion
analyses of the SRS gene superfamily identify SRS29C as a negative
regulator of Toxoplasma
virulence. mBio 3(6).
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Commentary:
Walzer KA and Boyle JP.
(2012) A single chromosome unexpectedly links highly divergent isolates
of Toxoplasma gondii.
mBio 3(1):e00284-11. |
| 2011 |
Kamau
E, Meehan T, Lavine MD, Arrizabalaga G, Mustata Wilson G, and Boyle
JP. (2011) A novel
benzodioxole-containing inhibitor of Toxoplasma
gondii growth alters the
parasite cell cycle. Antimicrobial Agents & Chemotherapy 55:5438-5451. |
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Reese
ML, Zeiner GM, Saeij JP, Boothroyd JC, and Boyle
JP.
(2011) Polymorphic family of injected pseudokinases is paramount in Toxoplasma
virulence. Proc Natl Acad Sci U S A. 108:9625-9630.
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Ong
YC, Boyle JP,
and Boothroyd JC. (2011) Strain-dependent host transcriptional
responses to Toxoplasma
infection are largely conserved in mammalian and avian hosts. PLoS
ONE. 6:e26369.
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Review:
Adomako-Ankomah Y, Wier G and Boyle
JP.
(2011) Beyond the genome: Recent advances in Toxoplasma
gondii functional
genomics. Parasite Immunology. 55(12):5438-51. |
| 2010 |
Khaminets
A, Hunn JP, Konen-Waisman S, Zhao YO, Preukschat D, Coers J, Boyle
JP, Ong YC, Boothroyd JC,
Reichmann G, and Howard JC. (2010) Coordinated loading of IRG
resistance GTPases on to the Toxoplasma
gondii parasitophorous vacuole.
Cellular Microbiology. 12:939-961.
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| 2009 |
Bontell
IL, Hall N, Ashelford KE, Dubey JP, Boyle
JP, Lindh J, and Smith JE.
(2009) Whole genome sequencing of a natural recombinant Toxoplasma
gondii strain reveals
chromosome sorting and local allelic variants. Genome Biology 10:R53.
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Review:
Boyle JP and Radke J.
(2009) A brief history of studies that examine the
interactions of Toxoplasma
with its host cell: Emphasis on in
vitro models.
International Journal for Parasitology. 39:903-914. |
| 2008 |
Boyle
JP, Saeij JP, Harada SY,
Ajioka JW, and Boothroyd JC. (2008) Expression quantitative trait locus
mapping of Toxoplasma
genes reveals multiple mechanisms for strain-specific differences in
gene expression. Eukaryotic Cell. 7:1403-1414.
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| 2007 |
Boyle
JP,
Saeij JP, and Boothroyd JC. (2007) Toxoplasma
gondii: inconsistent
dissemination patterns following oral infection in mice. Experimental
Parasitology. 116:302-305.
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Saeij
JP, Coller S, Boyle JP,
Jerome ME, White MW, and Boothroyd JC. (2007) Toxoplasma
co-opts host gene expression by injection of a polymorphic kinase
homologue. Nature. 445:324-327.
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| 2006 |
Boyle
JP, Rajasekar B, Saeij JP,
Ajioka JW, Berriman M, Paulsen I, Roos DS, Sibley LD, White MW, and
Boothroyd JC. (2006) Just one cross appears capable of dramatically
altering the population biology of a eukaryotic pathogen like Toxoplasma
gondii. Proc Natl Acad Sci U S
A. 103:10514-10519.
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Saeij
JP, Boyle JP,
Coller S, Taylor S, Sibley LD, Brooke-Powell ET, Ajioka JW, and
Boothroyd JC. (2006) Polymorphic secreted kinases are key virulence
factors in toxoplasmosis. Science. 314:1780-1783.
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Review:
Boyle JP, Saeij JPJ, Cleary
MD and Boothroyd JC. (2006) Analysis of gene expression
during development: lessons from the Apicomplexa. Microbes
and Infection. 8(6):1623-30. |
| 2005 |
Boyle
JP, and Yoshino TP. (2005)
Serotonin-induced muscular activity in Schistosoma
mansoni larval stages:
importance of 5-HT transport and role in daughter sporocyst production.
Journal of Parasitology. 91:542-550.
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Hillyer
JF, Schmidt SL, Fuchs JF, Boyle
JP, and Christensen BM.
(2005) Age-associated mortality in immune challenged mosquitoes (Aedes
aegypti) correlates with a
decrease in haemocyte numbers. Cellular Microbiology. 7:39-51.
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Khan
A, Taylor S, Su C, Mackey AJ, Boyle
J, Cole R, Glover D, Tang
K, Paulsen IT, Berriman M, Boothroyd JC, Pfefferkorn ER, Dubey JP,
Ajioka JW, Roos DS, Wootton JC, and Sibley LD. (2005) Composite genome
map and recombination parameters derived from three archetypal lineages
of Toxoplasma gondii.
Nucleic Acids Research. 33:2980-2992.
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Saeij
JP, Boyle JP,
Grigg ME, Arrizabalaga G, and Boothroyd JC. (2005) Bioluminescence
imaging of Toxoplasma gondii
infection in living mice reveals dramatic differences between strains.
Infection and Immunity. 73:695-702.
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Review:
Saeij JPJ, Boyle JP
and Boothroyd JC. (2005) Differences among the three major
strains of Toxoplasma gondii
and their specific interactions with the infected host.
Trends in Parasitology. 21(10):476-81. |
| 2004 |
Bartholomay
LC, Cho WL, Rocheleau TA, Boyle
JP, Beck ET, Fuchs JF, Liss
P, Rusch M, Butler KM, Wu RC, Lin SP, Kuo HY, Tsao IY, Huang CY, Liu
TT, Hsiao KJ, Tsai SF, Yang UC, Nappi AJ, Perna NT, Chen CC, and
Christensen BM. (2004) Description of the transcriptomes of immune
response-activated hemocytes from the mosquito vectors Aedes
aegypti and Armigeres
subalbatus. Infection and
Immunity. 72:4114-4126.
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Vermeire
JJ, Boyle JP,
and Yoshino TP. (2004) Differential gene expression and the effects of Biomphalaria
glabrata embryonic (Bge) cell
factors during larval Schistosoma
mansoni development. Molecular
and Biochemical Parasitology. 135:153-157.
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| 2003 |
Boyle
JP, Hillyer JF, and Yoshino
TP. (2003) Pharmacological and autoradiographical characterization of
serotonin transporter-like activity in sporocysts of the human blood
fluke, Schistosoma mansoni.
Journal of Comparative Physiology A. 12:12.
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Boyle
JP, Wu XJ, Shoemaker CB,
and Yoshino TP. (2003) Using RNA interference to manipulate endogenous
gene expression in Schistosoma
mansoni sporocysts. Molecular
and Biochemical Parasitology. 128:205-215.
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Review:
Boyle JP
and Yoshino TP (2003) Gene manipulation of parasitic
helminths. International Journal for Parasitology.
33(11):1259-1268. |
| 2002 |
Boyle
JP, and Yoshino TP. (2002)
Monoamines in the albumen gland, plasma, and central nervous system of
the snail Biomphalaria
glabrata during egg-laying.
Comparative Biochemistry and Physiology A. 132:411-422.
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| 2001 |
Review:
Yoshino TP, Boyle
JP and Humphries JE
(2001) Receptor-ligand interactions and cellular signaling at
the host-parasite interface. Parasitology, 123:S143-157. |
| 2000 |
Boyle
JP, Zaide JV, and Yoshino
TP. (2000) Schistosoma mansoni:
effects of serotonin and serotonin receptor antagonists on motility and
length of primary sporocysts in
vitro. Experimental
Parasitology. 94:217-226. |
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Boyle
JP and Yoshino TP. (2000)
THE EFFECT OF WATER QUALITY ON OVIPOSITION IN BIOMPHALARIA
GLABRATA (SAY, 1818)
(PLANORBIDAE), AND A DESCRIPTION OF THE STAGES OF THE EGG-LAYING
PROCESS. Journal of Molluscan Studies. 66(1):83-94. Link
to article. |
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