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For CKD patients – no RCTs
•Hydrochloroquine(Plaquenil)
dose reduction if GFR< 30
•Beware
of interaction with other drugs, dose adjustments of CNI
(mainly ciclosporin), mTOR inhibitors
•Side
effects – often after long-term therapy
•Azithromycin
•
•Remdesivir
contraindicated if GFR<30
•
•Tocilizumab
(IL6 inhibition) – used for RA and vasculitis. Little
experience in dialysis but usually given as single dose
•
•CCRT
with techniques facilitating cytokine absorbtion, Cytosorb
|