Journal Publications

2025

Chen M, Sheng Z, Wei R, Zhang B, Kim H, Wu H, Chu Y, Chen Q, Breon A, Li S, Wielgat MB, Shanmuganayagam D, Tzeng E, Geng X, Kim K, Jiang X. Millisecond-level transient heating and temperature monitoring technique for ultrasound-induced thermal strain imaging. Theranostics 2025; 15(3):815-827. doi:10.7150/thno.95997.

Z. Sheng, E. Bedoy, B. Dicianno, D. Weber, K. Kim. Image-Derived Skeletal Muscle Activation Metric Map: a Forearm Study Using Ultra-Fast Ultrasound Imaging and High-Density Electromyography. IEEE Transactions on Biomedical Engineering, vol. 72, no. 1, pp. 24-34, Jan. 2025, doi: 10.1109/TBME.2024.3436053. (Featured article in the TBME January Issue, 2025)

2024

Jing J. Zhang, Rodrigue Rizk, Xiaoping Li, Brandon G. Lee, Mason L. Matthies, Kennedy A. Bietz, Kang Kim, Johnny Huard, Yadong Wang, William C.W. Chen, Interleukin-10 Exhibit Dose-Dependent Effects on Macrophage Phenotypes and Cardiac Remodeling After Myocardial Infarction. Frontiers in Physiology, doi: 10.3389/fphys.2024.1481460. Accepted

Qiyang Chen, Michael W George, Brenda McMahon, Joshua A. Rosenthal, Kang Kim, Roderick J. Tan. Super-Resolution Ultrasound to Assess Kidney Vascular Changes in Humans with Kidney Disease. American Journal of Kidney Diseases, 2024, ISSN 0272-6386, doi: https://doi.org/10.1053/j.ajkd.2024.06.021.

Min Gon Kim, Kai Yu, Chih-Yu Yeh, Raghda Fouda, Donovan Argueta, Stacy Kiven, Yunruo Ni, Xiaodan Niu, Qiyang Chen, Kang Kim, Kalpna Gupta, Bin He. Low-intensity transcranial focused ultrasound suppresses pain by modulating pain processing brain circuits. Blood. 2024 Jul 8:blood.2023023718. doi: 10.1182/blood.2023023718.

Qiyang Chen, Rimi Hazra, Danielle Crosby, Diane Lenhart, Shane C Lenhart, Paritosh Mondal, Yingze Zhang, Seyed Mehdi Nouraie, Roderick J Tan, Charles Esmon, L. Vijaya Mohan Rao, Kang Kim, Samit Ghosh. Heme induced loss of renovascular endothelial protein C receptor promotes chronic kidney disease in sickle mice. Blood 2024; blood.2023023528. doi: https://doi.org/10.1182/blood.2023023528

Qiyang Chen, Fang-Wei Liu, Sung Kwon Cho, Kang Kim. 3-D real-time ultrasound tracking of acoustically actuated swimming microdrone. Sci Rep 14, 1547 (2024). https://doi.org/10.1038/s41598-024-52044-0

John M Cormack, Yu-hsuan Chao, Branch T Archer, Kang Kim, Kyle S. Spratt, Mark F. Hamilton. Focused shear wave beam propagation in tissue-mimicking phantoms. IEEE Transactions on Biomedical Engineering, vol. 71, no. 2, pp. 621-630, Feb. 2024, doi: 10.1109/TBME.2023.3311688. (Featured article in the TBME February Issue, 2024)

2023

Timothy N. Bachman, S. M. Nouraie, L. E. Williams, M. L. Boisen3, Kang Kim, H. S. Borovetz,R. Schaub, R. L. Kormos, M. A. Simon. Feasibility of a Composite Measure of Pulmonary Vascular Impedance and Application to Patients with Chronic RV Failure Post LVAD Implant. Cardiovascular Engineering and Technology. December 2023

Branch T. Archer, Yu-hsuan Chao, John M. Cormack, Kang Kim, Kyle S. Spratt, Mark F. Hamilton. Longitudinal motion of focused shear wave beams in soft elastic media. JASA February 2023;153, 1591. https://doi.org/10.1121/10.0017434

John M Cormack, Marc A Simon, Kang Kim. Backscatter tensor imaging and 3D speckle tracking for simultaneous ex vivo structure and deformation measurement of myocardium. Ultrasound Med Biol. February 2023;S0301-5629(23)00022-4. PubMed PMID: 36858914.

2022

Cormack J, Simon M, and Kim K. Refraction-corrected backscatter tensor imaging of excised porcine ventricular myocardium. JASA Express Letters 2, 092001 (2022). https://doi.org/10.1121/10.0014034

Sheng Z, Iyer A, Sun Z, Kim K, Sharma N. A Hybrid Knee Exoskeleton Using Real-Time Ultrasound-Based Muscle Fatigue Assessment. IEEE/ASME Transactions on Mechatronics, vol. 27, no. 4, pp. 1854-1862, Aug. 2022, doi: 10.1109/TMECH.2022.3171086.

Zhang Q, Iyer A, Lambeth K, Kim K, Sharma N. Ultrasound Echogenicity as an Indicator of Muscle Fatigue during Functional Electrical Stimulation. Sensors 2022;22, 335.

Sharifi Kia D, Shen Y, Bachman TN, Goncharova EA, Kim K, Simon MA. The Effects of Healthy Aging on Right Ventricular Structure and Biomechanical Properties: A Pilot Study. Front. Med January 2022;l8,751338

2021

Khalid WB, Farhat N, Lavery L, Jarnagin J, Delany JP, Kim K. Non-invasive assessment of liver fat in ob/ob mice using ultrasound-induced thermal strain imaging and its correlation with hepatic triglyceride content. Ultrasound Med Biol. 2021 Apr;47(4):1067-76. PubMed PMID: 33468357.

Sheng Z, Smith J, Kim K†. Current status and advancement of ultrasound imaging technologies in musculoskeletal studies. Curr Phys Med Rehabil Rep. [Current Physical Medicine and Rehabilitation Reports https://doi.org/10.1007/s40141-021-00337-0

Zhang Q, Iyer A, Sun Z, Kim K, Sharma N. A Dual-modal Approach Using Electromyography and Sonomyography Improves Prediction of Dynamic Ankle Movement: A Case Study. IEEE Trans Neural Syst Rehabil Eng. 2021 Aug. PubMed PMID: 3442814. [Epub ahead of print]

Khalid WB, Chen X, Kim K Multifocus thermal strain imaging using a curved linear array transducer for identification of lipids in deep tissue Ultrasound Med Biol. 2021 Apr;S0301-5629(21)00126-5. PubMed PMID: 33931283. [Epub ahead of print]

Bachman T, Kim K, Simon M Semi-Automated Graphical System for Calculating Pulmonary Vascular Impedances in a Clinical Setting IEEE Open J Eng Med Biol. 2021 May. [Epub ahead of print]

Chen Q, Song H, Yu J, Kim K Current development and applications of super-resolution ultrasound imaging Sensors (Basel). 2021 Apr;21(7):2417.

Sharifi Kia D, Kim K, Simon MA Current Understanding of the Right Ventricle Structure and Function in Pulmonary Arterial Hypertension Front Physiol. 2021. [accepted]

2020

Sharifi Kia D, Benza E, Bachman TN, Tushak C, Kim K, Simon MA Angiotensin Receptor‐Neprilysin Inhibition Attenuates Right Ventricular Remodeling in Pulmonary Hypertension J Am Heart Assoc. 2020 Jun 18;e015708. 9(13), e015708. PubMed PMID: 32552157.

Sheng Z, Sharma N, Kim K Ultra-High-Frame-Rate Ultrasound Monitoring of Muscle Contractility Changes Due to Neuromuscular Electrical Stimulation. Ann Biomed Eng. 2020 Jun 1. PubMed PMID: 32483747. [Epub ahead of print]

Chen Q, Yu J, Rush BM, Stocker SD, Tan RJ, Kim K Ultrasound super-resolution imaging provides a noninvasive assessment of renal microvasculature changes during mouse acute kidney injury. Kidney Int. 2020. August; 98(2):355-365.

Capasso TL, Li B, Volek HJ, Khalid W, Rochon ER, Anbalagan A, Herdman C, Yost HJ, Villanueva FS, Kim K, Roman BL BMP10-mediated ALK1 signaling is continuously required for vascular development and maintenance. Angiogenesis. 2020 May;23(2):203-20. PubMed PMID: 31828546.

Sheng Z, Sharma N, Kim K Quantitative Assessment of Changes in Muscle Contractility Due to Fatigue During NMES: An Ultrasound Imaging Approach. IEEE Trans Biomed Eng. 2020 Mar;67(3):832-41. PubMed PMID: 31180832. (featured articlein the TBME March Issue, 2020)

Chen Q, Yu J, Lukashova L, Latoche JD, Zhu J, Lavery L, Verdelis K, Anderson C, Kim K Validation of ultrasound super-resolution imaging of vasa vasorum in rabbit atherosclerotic plaques. IEEE Trans Ultrason Ferroelectr Freq Control. 2020 Feb 18. [Epub ahead of print] PubMed PMID: 32086204.

Zhang Q, Kim K, Sharma N Prediction of Ankle Dorsiflexion Moment by Combined Ultrasound Sonography and Electromyography. IEEE Trans Neural Syst Rehabil Eng. 2020 Jan;28(1):318-27. PubMed PMID: 31725385.

2019

Amin MN, Rushdi MA, Marzaban RN, Yosry A, Kim K, Mahmoud AM Wavelet-based computationally-efficient computer-aided characterization of liver steatosis using conventional B-mode ultrasound images Biomed Signal Process Control 2019; 52:84-96.

Wang Z, Long DW, Chen WC, Kim K, Wang Y Decellularized Neonatal Cardiac Extracellular Matrix Prevents Widespread Ventricular Remodeling in Adult Mammals after Myocardial Infarction. Acta Biomater 2019;87:140-151.

Chen Q, Liu F-W, Xiao Z, Sharma N, Cho SK, and Kim K Ultrasound Tracking of the Acoustically Actuated Microswimmer. IEEE Transactions on Biomedical Engineering, pp. 1-1, 2019.

2018

Yu J, Pin S, Lin X, Su M, Bai M, and Kim K Photostable, hydrophilic, and near infrared quaterrylene-based dyes for photoacoustic imaging. Materials Science and Engineering: C, vol. 93, pp. 1012-1019, 2018.

Yu J, Lavery L, and Kim K Super-resolution ultrasound imaging method for microvasculature in vivo with a high temporal accuracy. Scientific Reports, vol. 8, no. 1, 2018.

Yu J, Nguyen HNY, Steenbergen W, and Kim K Recent Development of Technology and Application of Photoacoustic Molecular Imaging Toward Clinical Translation. Journal of Nuclear Medicine, vol. 59, no. 8, pp. 1202-1207, 2018.

Chen Q, Yu J, Kim K Review: optically-triggered phase-transition droplets for photoacoustic imaging. Biomed. Eng. Lett. (2018) 8: 223. https://doi.org/10.1007/s13534-018-0069-0

2017

Yu J, Schuman J, Lee J-K, Lee SG, Chang JH, Kim K A light illumination enhancement device for photoacoustic imaging: in vivo animal study. IEEE Trans Ultrason Ferroelectr Freq Control 2017 (featured on the front cover); 64(8):1205-1211; doi: 10.1109/TUFFC.2017.2713599

Desmidt T, Brizard B, Dujardin P-A, Ternifi R, Remenieras J-P, Patat F, Andersson F, Cottier J-P, Vierron E, Gissot V, Kim K, Aizenstein H, El-Hage W, and Camus V Brain Tissue Pulsatility is increased in mid-life depression: a comparative study using Ultrasound Tissue Pulsatility Imaging. Neuropsychopharmacology 2017;1-8; doi: 10.1038/npp.2017.113

Awada HK, Long DW, Wang Z, Hwang MP, Kim K, Wang Y A Single Injection of Protein-loaded Coacervate-Gel Significantly Improves Cardiac Function Post Infarction. Biomaterials 2017;125:65-80

Nguyen M, Ding X, Leers SA, Kim K Multi-foci beamforming for thermal strain imaging using a single ultrasound linear array transducer. Ultrasound Med Biol 2017;43(6)2:1263-1274; NIHMS848222

2016

Yu J, Chen X, Villanueva FS, Kim K Vaporization and recondensation dynamics of indocyanine green-loaded perfluoropentane droplets irradiated by a short pulse laser. Appl. Phys. Lett. 109, 243701 (2016); doi: 10.1063/1.4972184

Rubin JM, Horowitz JC, Sisson TH, Kim K, Ortiz LA, Hamilton JD Ultrasound Strain Measurements for Evaluating Local Pulmonary Ventilation. Ultrasound Med Biol 2016;42(11):2525-2531

Chen WCW, Wang Z, Missinato MA, Park DW, Long DW, Liu H-J, Zeng X, Yates NA, Kim K, Wang Y Decellularized Zebrafish Cardiac Extracellular Matrix Induces Mammalian Heart Regeneration.2016 Science Advances, 18 Nov 2016, Vol. 2, No. 11, e1600844

Park DW, Sebastiani A, Yap CH, Simon MA, Kim K Quantification of Coupled Stiffness and Fiber Orientation Remodeling in Hypertensive Rat Right-Ventricular Myocardium Using 3D Ultrasound Speckle Tracking with Biaxial Testing. 2016 PLoS ONE 11(10): e0165320. doi:10.1371/journal.pone.0165320, PMID: 27780271 PMCID: PMC5079565

Kim K, William RW, Non-invasive and non-destructive characterization of tissue engineered constructs using ultrasound imaging technologies: a review. Ann Biomed Eng (2016) 44: 621. doi:10.1007/s10439-015-1495-0

Ding X, Nguyen M, James I, Marra K, Rubin J. P, Leers SA, Kim K Improved Estimation of Ultrasound Thermal Strain Using Pulse Inversion Harmonic Imaging. Ultrasound in Medicine and Biology 2016 May;42:1182-1192.

2015

Lannau B, Bliley J, James IB, Wang S, Sivak W, Kim K, Fowler J, Spiess AM, Long-term Patency of Primary Arterial Repair and the Modified Cold Intolerance Symptom Severity Questionnaire. PRS. 2015 Nov;Vol 3(11):p e551

Chen WCW, Lee BG, Park DW, Kim K, Chu H, Kim K, Huard J, Wang Y, Controlled Dual Delivery of Fibroblast Growth Factor-2 and Interleukin-10 by Heparin-based Coacervate Synergistically Enhances Ischemic Heart Repair. Biomaterials. 2015;72:138-151, PMID: 26370927, PMCID: PMC4617784

Ding X, Dutta D, Mahmoud AM, Tillman B, Leers SA, Kim K. An Adaptive Displacement Estimation Algorithm for Improved Reconstruction of Thermal Strain. IEEE Trans Ultrason Ferroelectr Freq Control 2015;62(1):138-151, PMID: 25585398; PMCID: PMC4295651.

Yap CH, Park DW, Dutta D, Simon M, Kim K. Methods for Using 3D Ultrasound Speckle Tracking in Biaxial Mechanical Testing of Biological Tissue Samples. Ultrasound Med Biol 2015; 41(4):1029-1042, PMID:25616585.

Wang M, Dutta D, Kim K, Brigham J. A Computationally Efficient Approach for Inverse Material Characterization Combining Gappy POD with Direct Inversion. Comput Methods Appl. Mech. Engrg. 2015;286:373-393.

Kang J, Chang JH, Wilson B, Veilleux I, Bai Y, DaCosta R, Kim K, Ha S, Lee JG, Kim JS, Lee S-G, Kim SM, Lee HJ, Ahn YB, Han S, Yoo Y, and Song T-K. A prototype hand-held tri-modal instrument for in vivo ultrasound, photoacoustic and fluorescence imaging. Rev. Sci. Instrum. 2015; 86, 034901:1-13.

2014

Park D, Ye S, Jiang H, Dutta D, Nonakad K, Wagner W and Kim K. In vivo monitoring of structural and mechanical changes of tissue scaffolds by multi-modality imaging. Biomaterials, 2014, September, Vol. 35, Issue 27, 7851-7859.

Kagan V.E, Kapralov A, St Croix CM, Watkins S, Kisin E, Kotchey G, Balasubramanian K, Yu J, Kim K, Seo W, Mallampalli R, Star A, Shvedova A. Lung Macrophages "Digest" Carbon Nanotubes Using a Superoxide/Peroxynitrite Oxidative Pathway. ACS Nano, 2014, Vol. 8, No. 6, 5610-5621, DOI: 10.1021/nn406484b.

Mahmoud A, Ding X, Dutta D, Singh VP and Kim K. Detecting hepatic steatosis using ultrasound-induced thermal strain imaging: an ex vivo animal studyPhysics in Medicine and Biology, 2014, Vol. 59, 881-895.

Allen RA, Wu W, Yao M, Dutta D, Duan X, Bachman TN, Champion HC, Donna B, Stolz DB, Robertson AM, Kim K, Isenberg JS and Wang Y. Nerve regeneration and elastin formation within poly(glycerol sebacate)-based synthetic arterial grafts one-year post-implantation in a rat model. Biomaterials 2014 Jan; Vol. 35, Issue 1:165-173

2013

Stephens DN, Mahmoud A, Ding X, Lucero S, Dutta D, Yu FTH, Chen X and Kim K Flexible Integration of Both High Imaging Resolution and High Power Arrays for Ultrasound-Induced Thermal Strain Imaging (US-TSI). IEEE Trans Ultrason Ferroelectr Freq Control 2013 Dec;Vol.60, Issue 12:2456-2656

Dutta D, Mahmoud A, Leers S and Kim K. Motion Artifact Reduction in Ultrasound Based Thermal Strain Imaging of Atherosclerotic Plaques using Time Series Analysis. IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control, 2013 Aug;Vol. 60, No. 8:1660-1668.

Dutta D, Lee K, Allen R, Wang Y, Brigham JC and Kim K. Non-invasive Monitoring of Mechanical Strength of Arterial Constructs During Cell Culture Using Ultrasound Elasticity Imaging. Ultrasound in Medicine and Biology 2013 Nov;39:2103-2115.

A. Mahmoud, D. Dutta, L. Lavery, D. Stephens, F. S. Villanueva and K. Kim. Noninvasive detection of lipids in atherosclerotic plaque using ultrasound thermal strain imaging: in vivo animal study. Journal of the American College of Cardiology, 2013 Nov;5, Vol. 62, Issue. 19:1804-1809.

Yu J, Takanari K, Hong Y, Lee K-W, Amoroso NJ, Wang Y, Wagner WR and Kim K. Non-invasive characterization of polyurethane-based tissue constructs in a rat abdominal repair model using high frequency ultrasound elasticity imaging. Biomaterials 2013;34(11):2701-2709, PMID:23347836, PMCID: PMC3565386.

Hollman KW, Shtein RM, Tripathy S and Kim K. Using an ultrasound elasticity microscope to map three-dimensional strain in a porcine cornea. Ultrasound Med Biol 2013 Aug;39:1451-1459.

2012

Xu J, Tripathy S, Rubin JM, Stidham RW, Johnson LA, Higgins PDR, Kim K. A new nonlinear parameter in the developed strain-to-applied strain of the soft tissues and its application in ultrasound elasticity imaging. Ultrasound Med Biol 2012;38(3):511-523, PMID: 22266232, PMCID: PMC3273568.

Kim JS, Leeman JE, Kagemann L, Yu F, Chen X, Pacella JJ, Schuman JS, Villanueva FS and Kim K. Volumetric quantification of in vitro sonothrombolysis with microbubbles using high resolution optical coherence tomography (OCT). J Biomed Optics 2012;17(7):070502 1-3.

Leeman JE, Kim JS, Yu F, Chen X, Kim K, Villanueva FS and Pacella JJ. Effect of acoustic conditions on microbubble-mediated microvascular sonothrombolysis. Ultrasound Med Biol 2012 Sep;38:1589-1598.

Ha S, Carson A, Kim K. Ferritin as a novel reporter gene for photoacoustic molecular imaging. Cytometry Part A 2012;81(10):910-5, PMID: 22949299.

Kotchey GP, Hasan SA, Kapralov AA, Ha S, Kim K, Shvedova AA, Kagan VE, Star A. A natural vanishing act: The enzyme-catalyzed degradation of carbon nanomaterials. Acc Chem Res 2012;45(10):1770-81, PMID:22824066.

Wang Z, Ha S and Kim K. A new design of light illumination scheme for deep tissue photoacoustic Imaging. Opt Express 2012;20(20):22649-22659, PMID: 23037414.

2011

Ha S, Carson A, Agarwal A, Kotov NA and Kim K. Detection and monitoring of the multiple inflammatory responses by photoacoustic molecular imaging using selectively targeted gold nanorods. Biomed Opt Express 2011;2(3):645-57, PMID: 21412469.

Stidham RW, Xu J, Johnson LA, Kim K, Moons DS, McKenna BJ, Rubin JM and Higgins PDR. Ultrasound elasticity imaging for detecting intestinal fibrosis and inflammation in rats and humans with Crohn's disease. Gastroenterology, 2011;141(3):819-82, PMID: 21784048.

Seo CH, Shi Y, Huang S-W, Kim K and O'Donnell M. Thermal strain imaging: a review. Interface Focus 2011;1:649-664