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This is an
interesting slide. It shows rubella notifications in specified parts of the USA
before
(1966-68) and after (1975-77) the introduction of vaccination for rubella in the
second year of life (in 1969). It illustrates the expected increase in age at infection:
in 1975-77, a larger proportion of cases were 15+ years (yellow numbers). Despite
this, the age-specific incidence
in persons aged 15+ years was lower in 1975-77
(red numbers) along with the total
incidence which was also lower
(bottom
line). This was a favourable outcome of immunisation: the (inevitable)
relative increase of
rubella occurrence in older age-groups was accompanied by an
absolute decrease. (Source of data: Preblud SR, Serdula MK, Frank JA, Brandling-Bennett AD, Hinman AR.
Rubella vaccination in the United States: a ten-year review.
Epidemiol Rev 1980;
2:171-94.)
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